Pemetrexed Disodium

Name: Pemetrexed Disodium
Brand: Vaqora Chemicals
SKU: VQ-007647

About Pemetrexed Disodium

Listed under CAS 150399-23-8, Pemetrexed Disodium is a high-purity reference standard of Pemetrexed available from Vaqora Chemicals. Its molecular formula is C20H19N5Na2O6 and its molecular weight is 471.4 g/mol. It is also known as Pemetrexed sodium or Rolazar.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Pemetrexed, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Pemetrexed Disodium in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Pemetrexed

View every impurity, metabolite and intermediate we list for Pemetrexed.

Pemetrexed impurities

Specifications & identifiers

Chemical identifiers
Product name	Pemetrexed Disodium
Catalogue No.	VQ-007647
CAS Number	150399-23-8
Other CAS	137281-23-3
IUPAC name	disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
Molecular formula	C₂₀H₁₉N₅Na₂O₆
Molecular weight	471.4 g/mol
Exact mass	471.1131
Grade	Reference Standard
HSN code	38229090
InChIKey	NYDXNILOWQXUOF-GXKRWWSZSA-L
SMILES	C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
PubChem CID	135413520

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 7
TPSA	193 Å²
Synonyms	Pemetrexed sodium, Rolazar, Tifolar, Pemetrexed sodium salt, Disodium, Pemetrexed, Pemetrexed disodium (USAN), EX-A836

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H360May damage fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pemetrexed Disodium?

The CAS Registry Number of Pemetrexed Disodium is 150399-23-8. It is also known as Pemetrexed sodium, Rolazar, Tifolar.

What is the molecular formula and molecular weight of Pemetrexed Disodium?

Pemetrexed Disodium has the molecular formula C20H19N5Na2O6 and a molecular weight of 471.4 g/mol.

What is Pemetrexed Disodium used for?

Pemetrexed Disodium is supplied as a characterised reference material related to Pemetrexed. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pemetrexed Disodium can I order?

We supply Pemetrexed Disodium in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pemetrexed Disodium?

Yes. Every lot of Pemetrexed Disodium is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pemetrexed Disodium be shipped internationally?

Yes. Pemetrexed Disodium is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.