Pemetrexed Opened Ring Keto-Formamide

Name: Pemetrexed Opened Ring Keto-Formamide
Brand: Vaqora Chemicals
SKU: VQ-044583

About Pemetrexed Opened Ring Keto-Formamide

Pemetrexed Opened Ring Keto-Formamide (CAS 1644286-35-0) is an impurity of Pemetrexed offered by Vaqora Chemicals. Formula C20H21N5O8, molecular weight 459.4 g/mol. Its systematic (IUPAC) name is (2S)-2-[[4-[3-(2-amino-4-formamido-6-oxo-1H-pyrimidin-5-yl)-3-oxopropyl]benzoyl]amino]pentanedioic acid. It is also known as Pemetrexed seco-indolone or Pemetrexed Open-Ring N-Formyl Keto Amine.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Pemetrexed, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pemetrexed

View every impurity, metabolite and intermediate we list for Pemetrexed.

Pemetrexed impurities

Specifications & identifiers

Chemical identifiers
Product name	Pemetrexed Opened Ring Keto-Formamide
Catalogue No.	VQ-044583
CAS Number	1644286-35-0
IUPAC name	(2S)-2-[[4-[3-(2-amino-4-formamido-6-oxo-1H-pyrimidin-5-yl)-3-oxopropyl]benzoyl]amino]pentanedioic acid
Molecular formula	C₂₀H₂₁N₅O₈
Molecular weight	459.4 g/mol
Exact mass	459.139
Grade	Reference Standard
HSN code	38229090
InChIKey	ZQLFWLDXMXHPNR-LBPRGKRZSA-N
SMILES	C1=CC(=CC=C1CCC(=O)C2=C(N=C(NC2=O)N)NC=O)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	145709349

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.8
H-bond donors / acceptors	6 / 9
TPSA	217 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pemetrexed Opened Ring Keto-Formamide?

The CAS Registry Number of Pemetrexed Opened Ring Keto-Formamide is 1644286-35-0. It is also known as Pemetrexed seco-indolone, Pemetrexed Open-Ring N-Formyl Keto Amine.

What is the molecular formula and molecular weight of Pemetrexed Opened Ring Keto-Formamide?

Pemetrexed Opened Ring Keto-Formamide has the molecular formula C20H21N5O8 and a molecular weight of 459.4 g/mol. Its IUPAC name is (2S)-2-[[4-[3-(2-amino-4-formamido-6-oxo-1H-pyrimidin-5-yl)-3-oxopropyl]benzoyl]amino]pentanedioic acid.

What is Pemetrexed Opened Ring Keto-Formamide used for?

Pemetrexed Opened Ring Keto-Formamide is supplied as a characterised reference material related to Pemetrexed. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pemetrexed Opened Ring Keto-Formamide can I order?

We supply Pemetrexed Opened Ring Keto-Formamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pemetrexed Opened Ring Keto-Formamide?

Yes. Every lot of Pemetrexed Opened Ring Keto-Formamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pemetrexed Opened Ring Keto-Formamide be shipped internationally?

Yes. We export Pemetrexed Opened Ring Keto-Formamide worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.