Phthalic Hydrazide

Name: Phthalic Hydrazide
Brand: Vaqora Chemicals
SKU: VQ-027071

About Phthalic Hydrazide

Phthalic Hydrazide is an impurity of Rivaroxaban carrying the CAS registry number 1445-69-8. With the molecular formula C8H6N2O2, it has a molar mass of 162.15 g/mol. The IUPAC name is 2,3-dihydrophthalazine-1,4-dione. It is also known as Phthalhydrazide or 2,3-Dihydro-1,4-phthalazinedione.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Rivaroxaban, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Phthalic Hydrazide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rivaroxaban

View every impurity, metabolite and intermediate we list for Rivaroxaban.

Rivaroxaban impurities

Specifications & identifiers

Chemical identifiers
Product name	Phthalic Hydrazide
Catalogue No.	VQ-027071
CAS Number	1445-69-8
IUPAC name	2,3-dihydrophthalazine-1,4-dione
Molecular formula	C₈H₆N₂O₂
Molecular weight	162.15 g/mol
Exact mass	162.0429
Grade	Reference Standard
HSN code	38229090
InChIKey	KGLPWQKSKUVKMJ-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C(=O)NNC2=O
PubChem CID	219401

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	2 / 2
TPSA	58.2 Å²
Synonyms	Phthalhydrazide, 2,3-Dihydro-1,4-phthalazinedione, 1,4-Phthalazinedione, 2,3-dihydro-, 1,4-Phthalazinediol, 2,3-DHPD, Phthalocyclohydrazide, 1,2,3,4-tetrahydrophthalazine-1,4-dione, phthalazine-1,4-diol, Phthalazine-1,4(2H,3H)-dione, 4-hydroxyphthalazin-1(2H)-one, 2,3-dihydro-phthalazine-1,4-dione, 1,4-Dioxo-1,2,3,4-tetrahydrophthalazine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Phthalic Hydrazide?

The CAS Registry Number of Phthalic Hydrazide is 1445-69-8. It is also known as Phthalhydrazide, 2,3-Dihydro-1,4-phthalazinedione, 1,4-Phthalazinedione, 2,3-dihydro-.

What is the molecular formula and molecular weight of Phthalic Hydrazide?

Phthalic Hydrazide has the molecular formula C8H6N2O2 and a molecular weight of 162.15 g/mol. Its IUPAC name is 2,3-dihydrophthalazine-1,4-dione.

What is Phthalic Hydrazide used for?

Phthalic Hydrazide is supplied as a characterised reference material related to Rivaroxaban. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Phthalic Hydrazide can I order?

We supply Phthalic Hydrazide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Phthalic Hydrazide?

Yes. Every lot of Phthalic Hydrazide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Phthalic Hydrazide be shipped internationally?

Yes. Phthalic Hydrazide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.