Pizotyline

Name: Pizotyline
Brand: Vaqora Chemicals
SKU: VQ-041539

About Pizotyline

Pizotyline is an API impurity reference standard carrying the CAS registry number 15574-96-6. Its molecular formula is C19H21NS and its molecular weight is 295.4 g/mol. The IUPAC name is 1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine. It is also known as Pizotifen or Pizotifene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pizotyline in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Pizotyline
Catalogue No.	VQ-041539
CAS Number	15574-96-6
IUPAC name	1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine
Molecular formula	C₁₉H₂₁NS
Molecular weight	295.4 g/mol
Exact mass	295.1395
Grade	Reference Standard
HSN code	38229090
InChIKey	FIADGNVRKBPQEU-UHFFFAOYSA-N
SMILES	CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
PubChem CID	27400

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	0 / 2
TPSA	31.5 Å²
Synonyms	Pizotifen, Pizotifene, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine, BC 105, 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine, Piperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methyl-, Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-, 4-(9,10-Dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thien-4-ylidene)-1-methylpiperidine, 4-(9,10-dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thiophen-4-ylidene)-1-methylpiperidine, 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, BC-105, Pizotyline (USAN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pizotyline?

The CAS Registry Number of Pizotyline is 15574-96-6. It is also known as Pizotifen, Pizotifene, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine.

What is the molecular formula and molecular weight of Pizotyline?

Pizotyline has the molecular formula C19H21NS and a molecular weight of 295.4 g/mol. Its IUPAC name is 1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine.

Which grade and pack sizes of Pizotyline can I order?

We supply Pizotyline in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pizotyline?

Yes. Every lot of Pizotyline is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pizotyline be shipped internationally?

Yes. Pizotyline is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.