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Posacanzole Intermediate B

Synonyms: 4-[4-(4-aminophenyl)-1-piperazinyl]phenol · 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine · 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol · 4-(4-(4-aminophenyl)piperazin-1-yl)phenol

CAS No.74853-08-0
FormulaC16H19N3O
Mol. weight269.34
Catalogue No.VQ-013728
PurityReference Standard
HSN2933

Posacanzole Intermediate B (CAS 74853-08-0) – Posaconazole intermediate. C16H19N3O, MW 269.34. COA included. Worldwide shipping from Vaqora Chemicals.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
250 mg
500 mg
1 g
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About Posacanzole Intermediate B

Posacanzole Intermediate B (CAS 74853-08-0) is a process intermediate or related compound of Posaconazole offered by Vaqora Chemicals. With the molecular formula C16H19N3O, it has a molar mass of 269.34 g/mol. The IUPAC name is 4-[4-(4-aminophenyl)piperazin-1-yl]phenol. It is also known as 4-[4-(4-aminophenyl)-1-piperazinyl]phenol or 4-(4-(4-aminophenyl)piperazin-1-yl)phenol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Posaconazole, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Posacanzole Intermediate B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

  • API route development
  • Impurity fate & purge studies
  • Analytical method development

Industries

Related to Posaconazole

View every impurity, metabolite and intermediate we list for Posaconazole.

Posaconazole impurities

Specifications & identifiers

Chemical identifiers
Product namePosacanzole Intermediate B
Catalogue No.VQ-013728
CAS Number74853-08-0
IUPAC name4-[4-(4-aminophenyl)piperazin-1-yl]phenol
Molecular formulaC16H19N3O
Molecular weight269.34 g/mol
Exact mass269.1528
GradeReference Standard
HSN code2933
InChIKeyWZIJMPVPOMTRNM-UHFFFAOYSA-N
SMILESC1CN(CCN1C2=CC=C(C=C2)N)C3=CC=C(C=C3)O
PubChem CID10221065
Physical properties
Physical formSolid
LogP (XLogP3)2.6
H-bond donors / acceptors2 / 4
TPSA52.7 Ų
Synonyms4-[4-(4-aminophenyl)-1-piperazinyl]phenol, 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine, 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol, 4-(4-(4-aminophenyl)piperazin-1-yl)phenol, 4-(4-(4-Aminophenyl)-1-piperazinyl)phenol, Phenol, 4-[4-(4-aminophenyl)-1-piperazinyl]-, Posazonazole Intermediate 1, 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)- piperazine

Safety & hazard information (GHS)

GHS07 Harmful / irritant
Harmful / irritant

Signal word: Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Frequently asked questions

What is the CAS number of Posacanzole Intermediate B?

The CAS Registry Number of Posacanzole Intermediate B is 74853-08-0. It is also known as 4-[4-(4-aminophenyl)-1-piperazinyl]phenol, 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine, 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol.

What is the molecular formula and molecular weight of Posacanzole Intermediate B?

Posacanzole Intermediate B has the molecular formula C16H19N3O and a molecular weight of 269.34 g/mol. Its IUPAC name is 4-[4-(4-aminophenyl)piperazin-1-yl]phenol.

What is Posacanzole Intermediate B used for?

Posacanzole Intermediate B is supplied as a characterised reference material related to Posaconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Posacanzole Intermediate B can I order?

We supply Posacanzole Intermediate B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Posacanzole Intermediate B?

Yes. Every lot of Posacanzole Intermediate B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Posacanzole Intermediate B be shipped internationally?

Yes. Posacanzole Intermediate B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.

Enquire about Posacanzole Intermediate B

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Why buyers choose Vaqora

  • Batch-traceable lots with COA
  • R&D packs to multi-tonne supply
  • IATA / IMDG dangerous-goods packing
  • EXW, FOB, CIF, DAP Incoterms
  • Custom synthesis & sourcing
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