Pregnenolone-16-ene Acetate Oxime

Name: Pregnenolone-16-ene Acetate Oxime
Brand: Vaqora Chemicals
SKU: VQ-021378

About Pregnenolone-16-ene Acetate Oxime

Vaqora Chemicals supplies Pregnenolone-16-ene Acetate Oxime, an impurity of Abiraterone registered under CAS number 2174-13-2. The compound has the formula C23H33NO3, corresponding to a molecular weight of 371.5 g/mol. Alternative names: Abiraterone Pregnenolone-16-Ene Acetate Oxime.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Abiraterone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Pregnenolone-16-ene Acetate Oxime is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Abiraterone

View every impurity, metabolite and intermediate we list for Abiraterone.

Abiraterone impurities

Specifications & identifiers

Chemical identifiers
Product name	Pregnenolone-16-ene Acetate Oxime
Catalogue No.	VQ-021378
CAS Number	2174-13-2
IUPAC name	[(3S,8R,9S,10R,13S,14S)-17-[(E)-N-hydroxy-C-methylcarbonimidoyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
Molecular formula	C₂₃H₃₃NO₃
Molecular weight	371.5 g/mol
Exact mass	371.246
Grade	Reference Standard
HSN code	38229090
InChIKey	OVKSHCIVDWZSJD-PYABZAOMSA-N
SMILES	C/C(=N\O)/C1=CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OC(=O)C)C)C
PubChem CID	5484383

Physical properties
Physical form	Solid
LogP (XLogP3)	4.8
H-bond donors / acceptors	1 / 4
TPSA	58.9 Å²
Synonyms	Abiraterone Pregnenolone-16-Ene Acetate Oxime, 16-Dehydro Pregnenolone Acetate Oxime (DHPG Oxime Acetate), (20E)-3beta-Hydroxypregna-5,16-dien-20-one 20-oxime 3-acetate, 3beta-Acetoxy-pregna-5,16-diene-20-oxime, (E)-, (20E)-20-(Hydroxyimino)pregna-5,16-dien-3beta-yl acetate, (3I(2),20E)-3-(Acetyloxy)pregna-5,16-dien-20-one 20-oxime

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pregnenolone-16-ene Acetate Oxime?

The CAS Registry Number of Pregnenolone-16-ene Acetate Oxime is 2174-13-2. It is also known as Abiraterone Pregnenolone-16-Ene Acetate Oxime, 16-Dehydro Pregnenolone Acetate Oxime (DHPG Oxime Acetate), (20E)-3beta-Hydroxypregna-5,16-dien-20-one 20-oxime 3-acetate.

What is the molecular formula and molecular weight of Pregnenolone-16-ene Acetate Oxime?

Pregnenolone-16-ene Acetate Oxime has the molecular formula C23H33NO3 and a molecular weight of 371.5 g/mol. Its IUPAC name is [(3S,8R,9S,10R,13S,14S)-17-[(E)-N-hydroxy-C-methylcarbonimidoyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate.

What is Pregnenolone-16-ene Acetate Oxime used for?

Pregnenolone-16-ene Acetate Oxime is supplied as a characterised reference material related to Abiraterone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pregnenolone-16-ene Acetate Oxime can I order?

We supply Pregnenolone-16-ene Acetate Oxime in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pregnenolone-16-ene Acetate Oxime?

Yes. Every lot of Pregnenolone-16-ene Acetate Oxime is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pregnenolone-16-ene Acetate Oxime be shipped internationally?

Yes. Pregnenolone-16-ene Acetate Oxime is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.