Pretomanid

Name: Pretomanid
Brand: Vaqora Chemicals
SKU: VQ-027619

About Pretomanid

Vaqora Chemicals supplies Pretomanid, a high-purity reference standard of Pretomanid registered under CAS number 187235-37-6. Its molecular formula is C14H12F3N3O5 and its molecular weight is 359.26 g/mol. Systematically, it is named (6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine. Common synonyms include PA-824 and PA 824.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Pretomanid, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Pretomanid in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Pretomanid

View every impurity, metabolite and intermediate we list for Pretomanid.

Pretomanid impurities

Specifications & identifiers

Chemical identifiers
Product name	Pretomanid
Catalogue No.	VQ-027619
CAS Number	187235-37-6
IUPAC name	(6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
Molecular formula	C₁₄H₁₂F₃N₃O₅
Molecular weight	359.26 g/mol
Exact mass	359.0729
Grade	Reference Standard
HSN code	38229090
InChIKey	ZLHZLMOSPGACSZ-NSHDSACASA-N
SMILES	C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F
PubChem CID	456199

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	0 / 9
TPSA	91.3 Å²
Synonyms	PA-824, PA 824, 2-nitro-6-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine, (6S)-2-nitro-6-((4-(trifluoromethoxy)phenyl)methoxy)-5H,6H,7H-imidazo(2,1-b)(1,3)oxazine, (S)-2-Nitro-6-((4-(trifluoromethoxy)benzyl)oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, (S)-PA 824, (S)-PA 824 (Pretomanid), (S)-2-Nitro-6-[[4-(trifluoromethoxy)benzyl]oxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine, PA-824(Pretomanid), Pretomanid(S)-PA 824, EX-A1749

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Pretomanid?

The CAS Registry Number of Pretomanid is 187235-37-6. It is also known as PA-824, PA 824, 2-nitro-6-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine.

What is the molecular formula and molecular weight of Pretomanid?

Pretomanid has the molecular formula C14H12F3N3O5 and a molecular weight of 359.26 g/mol. Its IUPAC name is (6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine.

What is Pretomanid used for?

Pretomanid is supplied as a characterised reference material related to Pretomanid. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Pretomanid can I order?

We supply Pretomanid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Pretomanid?

Yes. Every lot of Pretomanid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Pretomanid be shipped internationally?

Yes. Pretomanid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.