Propane-1,3-diyl bis(4-methylbenzenesulfonate) 5469-66-9

Name: Propane-1,3-diyl bis(4-methylbenzenesulfonate)
Brand: Vaqora Chemicals
SKU: VQ-048630

About Propane-1,3-diyl bis(4-methylbenzenesulfonate)

Vaqora Chemicals supplies Propane-1,3-diyl bis(4-methylbenzenesulfonate), an impurity of Icotinib registered under CAS number 5469-66-9. The compound has the formula C17H20O6S2, corresponding to a molecular weight of 384.5 g/mol. Its systematic (IUPAC) name is 3-(4-methylphenyl)sulfonyloxypropyl 4-methylbenzenesulfonate. Common synonyms include 1,3-Bis(tosyloxy)propane and 1,3-Propanediol di-p-toluenesulfonate.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Icotinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Propane-1,3-diyl bis(4-methylbenzenesulfonate) is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Icotinib

View every impurity, metabolite and intermediate we list for Icotinib.

Icotinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Propane-1,3-diyl bis(4-methylbenzenesulfonate)
Catalogue No.	VQ-048630
CAS Number	5469-66-9
IUPAC name	3-(4-methylphenyl)sulfonyloxypropyl 4-methylbenzenesulfonate
Molecular formula	C₁₇H₂₀O₆S₂
Molecular weight	384.5 g/mol
Exact mass	384.0701
Grade	Reference Standard
HSN code	38229090
InChIKey	ODVREDGIWSDQFD-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)OCCCOS(=O)(=O)C2=CC=C(C=C2)C
PubChem CID	230370

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	0 / 6
TPSA	104 Å²
Synonyms	1,3-Bis(tosyloxy)propane, 1,3-Propanediol di-p-toluenesulfonate, 1,3-Propanediol di-p-tosylate, Trimethylene Glycol Ditosylate, 1,3-propanediyl di-p-toluenesulphonate, Trimethylene Glycol Bis(p-toluenesulfonate), 3-[(4-methylbenzenesulfonyl)oxy]propyl 4-methylbenzene-1-sulfonate, 1,3-Propanediol-di-4-tosylate, propane-1,3-di-Tos, 1,3-(Di-p-tosyl)propane

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Propane-1,3-diyl bis(4-methylbenzenesulfonate)?

The CAS Registry Number of Propane-1,3-diyl bis(4-methylbenzenesulfonate) is 5469-66-9. It is also known as 1,3-Bis(tosyloxy)propane, 1,3-Propanediol di-p-toluenesulfonate, 1,3-Propanediol di-p-tosylate.

What is the molecular formula and molecular weight of Propane-1,3-diyl bis(4-methylbenzenesulfonate)?

Propane-1,3-diyl bis(4-methylbenzenesulfonate) has the molecular formula C17H20O6S2 and a molecular weight of 384.5 g/mol. Its IUPAC name is 3-(4-methylphenyl)sulfonyloxypropyl 4-methylbenzenesulfonate.

What is Propane-1,3-diyl bis(4-methylbenzenesulfonate) used for?

Propane-1,3-diyl bis(4-methylbenzenesulfonate) is supplied as a characterised reference material related to Icotinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Propane-1,3-diyl bis(4-methylbenzenesulfonate) can I order?

We supply Propane-1,3-diyl bis(4-methylbenzenesulfonate) in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Propane-1,3-diyl bis(4-methylbenzenesulfonate)?

Yes. Every lot of Propane-1,3-diyl bis(4-methylbenzenesulfonate) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Propane-1,3-diyl bis(4-methylbenzenesulfonate) be shipped internationally?

Yes. We export Propane-1,3-diyl bis(4-methylbenzenesulfonate) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.