Propiolic Acid

Name: Propiolic Acid
Brand: Vaqora Chemicals
SKU: VQ-032545

About Propiolic Acid

Vaqora Chemicals supplies Propiolic Acid, an impurity of Acalabrutinib registered under CAS number 471-25-0. Formula C3H2O2, molecular weight 70.05 g/mol. The IUPAC name is prop-2-ynoic acid. Common synonyms include 2-Propynoic acid and Propargylic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Acalabrutinib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Acalabrutinib

View every impurity, metabolite and intermediate we list for Acalabrutinib.

Acalabrutinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Propiolic Acid
Catalogue No.	VQ-032545
CAS Number	471-25-0
IUPAC name	prop-2-ynoic acid
Molecular formula	C₃H₂O₂
Molecular weight	70.05 g/mol
Exact mass	70.0055
Grade	Reference Standard
HSN code	38229090
InChIKey	UORVCLMRJXCDCP-UHFFFAOYSA-N
SMILES	C#CC(=O)O
PubChem CID	10110

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²
Synonyms	2-Propynoic acid, Propargylic acid, Propynoic acid, Acetylenecarboxylic acid, Carboxyacetylene, Carboxy acetylene, Propiolic acidd, propinic acid, Acetylenemonocarboxylate, propiolate

Safety & hazard information (GHS)

Flammable

Corrosive

Toxic

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H301Toxic if swallowed
H310Fatal in contact with skin
H314Causes severe skin burns and eye damage

Precautionary statements: P210, P233, P240, P241, P242, P243, P260, P262, P264, P270, P280, P301 + P316, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P303 + P361 + P353, P304 + P340, P305 + P354 + P338, P316, P321, P330, P361 + P364, P363, P370 + P378

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 471-25-0

Extra Pure

Propiolic acid, extra pure >95%

CAS: 471-25-0
Formula: C₃H₂O₂
MW: 70.05 g/mol

VQ-019956

Frequently asked questions

What is the CAS number of Propiolic Acid?

The CAS Registry Number of Propiolic Acid is 471-25-0. It is also known as 2-Propynoic acid, Propargylic acid, Propynoic acid.

What is the molecular formula and molecular weight of Propiolic Acid?

Propiolic Acid has the molecular formula C3H2O2 and a molecular weight of 70.05 g/mol. Its IUPAC name is prop-2-ynoic acid.

What is Propiolic Acid used for?

Propiolic Acid is supplied as a characterised reference material related to Acalabrutinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Propiolic Acid can I order?

We supply Propiolic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Propiolic Acid?

Yes. Every lot of Propiolic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Propiolic Acid be shipped internationally?

Yes. Propiolic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.