Propofol

Name: Propofol
Brand: Vaqora Chemicals
SKU: VQ-027660

About Propofol

Propofol is a high-purity reference standard of Propofol carrying the CAS registry number 2078-54-8. Its molecular formula is C12H18O and its molecular weight is 178.27 g/mol. The IUPAC name is 2,6-di(propan-2-yl)phenol. Alternative names: Disoprofol and Fresofol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Propofol, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Propofol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Propofol

View every impurity, metabolite and intermediate we list for Propofol.

Propofol impurities

Specifications & identifiers

Chemical identifiers
Product name	Propofol
Catalogue No.	VQ-027660
CAS Number	2078-54-8
IUPAC name	2,6-di(propan-2-yl)phenol
Molecular formula	C₁₂H₁₈O
Molecular weight	178.27 g/mol
Exact mass	178.1358
Grade	Reference Standard
HSN code	38229090
InChIKey	OLBCVFGFOZPWHH-UHFFFAOYSA-N
SMILES	CC(C)C1=C(C(=CC=C1)C(C)C)O
PubChem CID	4943

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	1 / 1
TPSA	20.2 Å²
Synonyms	Disoprofol, Fresofol, Ampofol, 2,6-Bis(1-methylethyl)phenol, Phenol, 2,6-bis(1-methylethyl)-, 2,6 Diisopropylphenol, 2,6-bis(propan-2-yl)phenol, ICI 35,868, Phenol, 2,6-bis(1-methylethyl), ICI 35-868, Propofol MCT, Rapanofal

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Propofol?

The CAS Registry Number of Propofol is 2078-54-8. It is also known as Disoprofol, Fresofol, Ampofol.

What is the molecular formula and molecular weight of Propofol?

Propofol has the molecular formula C12H18O and a molecular weight of 178.27 g/mol. Its IUPAC name is 2,6-di(propan-2-yl)phenol.

What is Propofol used for?

Propofol is supplied as a characterised reference material related to Propofol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Propofol can I order?

We supply Propofol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Propofol?

Yes. Every lot of Propofol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Propofol be shipped internationally?

Yes. Propofol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.