Propofol-β-D-Glucuronide

Name: Propofol-β-D-Glucuronide
Brand: Vaqora Chemicals
SKU: VQ-033372

About Propofol-β-D-Glucuronide

Listed under CAS 114991-26-3, Propofol-β-D-Glucuronide is a metabolite or degradation product of Propofol available from Vaqora Chemicals. Formula C18H26O7, molecular weight 354.4 g/mol. Systematically, it is named (2S,3S,4S,5R,6S)-6-[2,6-di(propan-2-yl)phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid. Alternative names: Propofol Beta-D-Glucuronide and Propofol O-Glucuronide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Analytical teams use this compound to identify metabolites and degradants of Propofol, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Propofol

View every impurity, metabolite and intermediate we list for Propofol.

Propofol impurities

Specifications & identifiers

Chemical identifiers
Product name	Propofol-β-D-Glucuronide
Catalogue No.	VQ-033372
CAS Number	114991-26-3
IUPAC name	(2S,3S,4S,5R,6S)-6-[2,6-di(propan-2-yl)phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Molecular formula	C₁₈H₂₆O₇
Molecular weight	354.4 g/mol
Exact mass	354.1679
Grade	Reference Standard
HSN code	38229090
InChIKey	JZSJIASBMOIIKI-RUKPJNHUSA-N
SMILES	CC(C)C1=C(C(=CC=C1)C(C)C)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)O
PubChem CID	71751823

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	4 / 7
TPSA	116 Å²
Synonyms	Propofol Beta-D-Glucuronide, Propofol O-Glucuronide, Propofol Glucuronide, beta-D-Glucopyranosiduronic acid, 2,6-bis(1-methylethyl)phenyl, Propofol, A-D-Glucuronide, Propofol-glucuronide, Propofol-b-D-glucuronide, Propofol (beta)-D-Glucuronide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Propofol-β-D-Glucuronide?

The CAS Registry Number of Propofol-β-D-Glucuronide is 114991-26-3. It is also known as Propofol Beta-D-Glucuronide, Propofol O-Glucuronide, Propofol Glucuronide.

What is the molecular formula and molecular weight of Propofol-β-D-Glucuronide?

Propofol-β-D-Glucuronide has the molecular formula C18H26O7 and a molecular weight of 354.4 g/mol. Its IUPAC name is (2S,3S,4S,5R,6S)-6-[2,6-di(propan-2-yl)phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.

What is Propofol-β-D-Glucuronide used for?

Propofol-β-D-Glucuronide is supplied as a characterised reference material related to Propofol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Propofol-β-D-Glucuronide can I order?

We supply Propofol-β-D-Glucuronide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Propofol-β-D-Glucuronide?

Yes. Every lot of Propofol-β-D-Glucuronide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Propofol-β-D-Glucuronide be shipped internationally?

Yes. Propofol-β-D-Glucuronide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.