Quinapril Impurity 2 (Hydrochloride)

Name: Quinapril Impurity 2 (Hydrochloride)
Brand: Vaqora Chemicals
SKU: VQ-005676

About Quinapril Impurity 2 (Hydrochloride)

Quinapril Impurity 2 (Hydrochloride) (CAS 103733-30-8) is an impurity of Quinapril offered by Vaqora Chemicals at a purity of 93%. Its molecular formula is C17H18ClNO2 and its molecular weight is 303.8 g/mol. Systematically, it is named benzyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate. Hydrochloride. It is also known as Quinaprile Imp-I (Int-B) or Quinapril Bicyclic Acid Benzyl Ester.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Quinapril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Quinapril

View every impurity, metabolite and intermediate we list for Quinapril.

Quinapril impurities

Specifications & identifiers

Chemical identifiers
Product name	Quinapril Impurity 2 (Hydrochloride)
Catalogue No.	VQ-005676
CAS Number	103733-30-8
Other CAS	77497-96-2
IUPAC name	benzyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate;hydrochloride
Molecular formula	C₁₇H₁₈ClNO₂
Molecular weight	303.8 g/mol
Exact mass	303.1026
Grade	Reference Standard
Purity / assay	93%
HSN code	38229090
InChIKey	HYKDEPCVBMNYCM-NTISSMGPSA-N
SMILES	C1[C@H](NCC2=CC=CC=C21)C(=O)OCC3=CC=CC=C3.Cl
PubChem CID	2760577

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	38.3 Å²
Synonyms	Quinaprile Imp-I (Int-B), (S)-benzyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride, L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid benzyl ester hydrochloride, (S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid benzyl ester hydrochloride, Benzyl (3S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate Hydrochloride, Benzyl (3s)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate, HCl, benzyl (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride, (s)-l-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid benzyl ester hydrochloride, Quinapril Bicyclic Acid Benzyl Ester, (3S)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic Acid Phenylmethyl Ester Hydrochloride, Quinapril Impurity 6, CarboxylicAcidPhenylMethylEsterHydrochloride,QuinaprilHcl

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Quinapril Impurity 2 (Hydrochloride)?

The CAS Registry Number of Quinapril Impurity 2 (Hydrochloride) is 103733-30-8. It is also known as Quinaprile Imp-I (Int-B), (S)-benzyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride, L-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid benzyl ester hydrochloride.

What is the molecular formula and molecular weight of Quinapril Impurity 2 (Hydrochloride)?

Quinapril Impurity 2 (Hydrochloride) has the molecular formula C17H18ClNO2 and a molecular weight of 303.8 g/mol.

What is Quinapril Impurity 2 (Hydrochloride) used for?

Quinapril Impurity 2 (Hydrochloride) is supplied as a characterised reference material related to Quinapril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Quinapril Impurity 2 (Hydrochloride) can I order?

We supply Quinapril Impurity 2 (Hydrochloride) in Reference Standard (93%) grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Quinapril Impurity 2 (Hydrochloride)?

Yes. Every lot of Quinapril Impurity 2 (Hydrochloride) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Quinapril Impurity 2 (Hydrochloride) be shipped internationally?

Yes. Quinapril Impurity 2 (Hydrochloride) is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.