(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic… 181289-33-8

Name: (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid
Brand: Vaqora Chemicals
SKU: VQ-012775

About (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid

Vaqora Chemicals supplies (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid, a process intermediate or related compound of Pregabalin registered under CAS number 181289-33-8. Formula C9H17NO3, molecular weight 187.24 g/mol. The IUPAC name is (3R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid. Alternative names: (R)-3-(Carbamoylmethyl)-5-methylhexanoic acid and Isobutyl glutarmonoamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Pregabalin, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Pregabalin

View every impurity, metabolite and intermediate we list for Pregabalin.

Pregabalin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid
Catalogue No.	VQ-012775
CAS Number	181289-33-8
IUPAC name	(3R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid
Molecular formula	C₉H₁₇NO₃
Molecular weight	187.24 g/mol
Exact mass	187.1208
Grade	Reference Standard
InChIKey	NPDKTSLVWGFPQG-SSDOTTSWSA-N
SMILES	CC(C)C[C@H](CC(=O)N)CC(=O)O
PubChem CID	11084586

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	2 / 3
TPSA	80.4 Å²
Synonyms	(R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid, (R)-3-(Carbamoylmethyl)-5-methylhexanoic acid, (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid, R-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid, Isobutyl glutarmonoamide, Hexanoic acid, 3-(2-amino-2-oxoethyl)-5-methyl-, (3R)-, (3R)-3-(carbamoylmethyl)-5-methylhexanoic acid, Pregabalin USP RC Isobutylglutarmonoamide, Hexanoic acid, 3-(2-amino-2-oxoethyl)-5-methyl-, (R)-, PCI-6, (r)-3-isobutyl glutaric acid monoamide, (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoicacid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 181289-33-8

Pharma

(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic Acid (R-CMH)

CAS: 181289-33-8
Formula: C₉H₁₇NO₃
MW: 187.24 g/mol

VQ-012705

Frequently asked questions

What is the CAS number of (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid?

The CAS Registry Number of (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid is 181289-33-8. It is also known as (R)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid, (R)-3-(Carbamoylmethyl)-5-methylhexanoic acid, (R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid.

What is the molecular formula and molecular weight of (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid?

(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid has the molecular formula C9H17NO3 and a molecular weight of 187.24 g/mol. Its IUPAC name is (3R)-3-(2-amino-2-oxoethyl)-5-methylhexanoic acid.

What is (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid used for?

(R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid is supplied as a characterised reference material related to Pregabalin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid can I order?

We supply (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid?

Yes. Every lot of (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid be shipped internationally?

Yes. (R)-(-)-3-(Carbamoylmethyl)-5-methylhexanoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.