(R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-… 2486454-64-0

Name: (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione
Brand: Vaqora Chemicals
SKU: VQ-039637

About (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione

(R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione (CAS 2486454-64-0) is a metabolite or degradation product of Elagolix offered by Vaqora Chemicals. The compound has the formula C28H24F5N3O4, corresponding to a molecular weight of 561.5 g/mol. Common synonyms include Elagolix Hydroxylamine.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Elagolix, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Elagolix

View every impurity, metabolite and intermediate we list for Elagolix.

Elagolix impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione
Catalogue No.	VQ-039637
CAS Number	2486454-64-0
IUPAC name	5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3-[(2R)-2-(hydroxyamino)-2-phenylethyl]-6-methylpyrimidine-2,4-dione
Molecular formula	C₂₈H₂₄F₅N₃O₄
Molecular weight	561.5 g/mol
Exact mass	561.1687
Grade	Reference Standard
HSN code	38229090
InChIKey	BWTTXCQONVJTRS-QFIPXVFZSA-N
SMILES	CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NO)C4=C(C(=CC=C4)OC)F
PubChem CID	162610383

Physical properties
Physical form	Solid
LogP (XLogP3)	4.6
H-bond donors / acceptors	2 / 10
TPSA	82.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione?

The CAS Registry Number of (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione is 2486454-64-0. It is also known as Elagolix Hydroxylamine.

What is the molecular formula and molecular weight of (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione?

(R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione has the molecular formula C28H24F5N3O4 and a molecular weight of 561.5 g/mol. Its IUPAC name is 5-(2-fluoro-3-methoxyphenyl)-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3-[(2R)-2-(hydroxyamino)-2-phenylethyl]-6-methylpyrimidine-2,4-dione.

What is (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione used for?

(R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione is supplied as a characterised reference material related to Elagolix. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione can I order?

We supply (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione?

Yes. Every lot of (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione be shipped internationally?

Yes. We export (R)-5-(2-Fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.