(R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a… 927812-33-7

Name: (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol
Brand: Vaqora Chemicals
SKU: VQ-036896

About (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol

(R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol is an impurity of Efavirenz carrying the CAS registry number 927812-33-7. Its molecular formula is C13H11ClF3NO and its molecular weight is 289.68 g/mol. The IUPAC name is (2R)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Efavirenz to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol
Catalogue No.	VQ-036896
CAS Number	927812-33-7
IUPAC name	(2R)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
Molecular formula	C₁₃H₁₁ClF₃NO
Molecular weight	289.68 g/mol
Exact mass	289.0481
Grade	Reference Standard
HSN code	38229090
InChIKey	KEMUGFRERPPUHB-GFCCVEGCSA-N
SMILES	C1CC1C#C[C@@](C2=C(C=CC(=C2)Cl)N)(C(F)(F)F)O
PubChem CID	10891562

Physical properties
Physical form	Solid
LogP (XLogP3)	3.8
H-bond donors / acceptors	2 / 5
TPSA	46.3 Å²
Synonyms	(R)-5-Chloro-α-(cyclopropylethynyl)-2-amino-α-(trifluoromethyl) benzenemethanol, (R)-5-Chloro-alpha-(cyclopropylethynyl)-2-amino-alpha-(trifluoromethyl) benzenemethanol, (R)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol, (R)-2-(2-Amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol, (I+/-R)-2-Amino-5-chloro-I+/--(2-cyclopropylethynyl)-I+/--(trifluoromethyl)benzenemethanol

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol?

The CAS Registry Number of (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol is 927812-33-7. It is also known as (R)-5-Chloro-α-(cyclopropylethynyl)-2-amino-α-(trifluoromethyl) benzenemethanol, (R)-5-Chloro-alpha-(cyclopropylethynyl)-2-amino-alpha-(trifluoromethyl) benzenemethanol, (R)-2-(2-Amino-5-chloro-phenyl)-4-cyclopropyl-1,1,1-trifluoro-but-3-yn-2-ol.

What is the molecular formula and molecular weight of (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol?

(R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol has the molecular formula C13H11ClF3NO and a molecular weight of 289.68 g/mol. Its IUPAC name is (2R)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol.

What is (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol used for?

(R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol can I order?

We supply (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol?

Yes. Every lot of (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol be shipped internationally?

Yes. We export (R)-5-Chloro-a-(cyclopropylethynyl)-2-amino-a-(trifluoromethyl) benzenemethanol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.