(R)-Laudanosine

Name: (R)-Laudanosine
Brand: Vaqora Chemicals
SKU: VQ-021679

About (R)-Laudanosine

(R)-Laudanosine (CAS 85-63-2) is an impurity of Cisatracurium offered by Vaqora Chemicals. The compound has the formula C21H27NO4, corresponding to a molecular weight of 357.4 g/mol. Systematically, it is named (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline. It is also known as (-)-Laudanosine or D-Laudanosine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Cisatracurium, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies (R)-Laudanosine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cisatracurium

View every impurity, metabolite and intermediate we list for Cisatracurium.

Cisatracurium impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Laudanosine
Catalogue No.	VQ-021679
CAS Number	85-63-2
IUPAC name	(1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
Molecular formula	C₂₁H₂₇NO₄
Molecular weight	357.4 g/mol
Exact mass	357.194
Grade	Reference Standard
HSN code	38229090
InChIKey	KGPAYJZAMGEDIQ-QGZVFWFLSA-N
SMILES	CN1CCC2=CC(=C(C=C2[C@H]1CC3=CC(=C(C=C3)OC)OC)OC)OC
PubChem CID	978314

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 5
TPSA	40.2 Å²
Synonyms	(-)-Laudanosine, D-Laudanosine, O-Methyllaudanidine, Laudanosine, (R)-, (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, (R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinoline, (1R)-1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, (R)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline, (R)-N-methyltetrahydropapaverine, (1R)-6,7-Dimethoxy-1-[(3,4-dimethoxyphenyl)methyl]-2-methyl-1,2,3,4-tetrahydroisoquinoline

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Laudanosine?

The CAS Registry Number of (R)-Laudanosine is 85-63-2. It is also known as (-)-Laudanosine, D-Laudanosine, O-Methyllaudanidine.

What is the molecular formula and molecular weight of (R)-Laudanosine?

(R)-Laudanosine has the molecular formula C21H27NO4 and a molecular weight of 357.4 g/mol. Its IUPAC name is (1R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline.

What is (R)-Laudanosine used for?

(R)-Laudanosine is supplied as a characterised reference material related to Cisatracurium. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Laudanosine can I order?

We supply (R)-Laudanosine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Laudanosine?

Yes. Every lot of (R)-Laudanosine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Laudanosine be shipped internationally?

Yes. We export (R)-Laudanosine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.