(R)-Sitagliptin Methyl-Ester Hydrochloride 1374985-05-3

Name: (R)-Sitagliptin Methyl-Ester Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-028055

About (R)-Sitagliptin Methyl-Ester Hydrochloride

(R)-Sitagliptin Methyl-Ester Hydrochloride (CAS 1374985-05-3) is an impurity of Sitagliptin offered by Vaqora Chemicals. With the molecular formula C11H13ClF3NO2, it has a molar mass of 283.67 g/mol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Sitagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (R)-Sitagliptin Methyl-Ester Hydrochloride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	(R)-Sitagliptin Methyl-Ester Hydrochloride
Catalogue No.	VQ-028055
CAS Number	1374985-05-3
IUPAC name	methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate;hydrochloride
Molecular formula	C₁₁H₁₃ClF₃NO₂
Molecular weight	283.67 g/mol
Exact mass	283.0587
Grade	Reference Standard
HSN code	38229090
InChIKey	HZHUQANPVYGJKF-OGFXRTJISA-N
SMILES	COC(=O)C[C@@H](CC1=CC(=C(C=C1F)F)F)N.Cl
PubChem CID	68750712

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 6
TPSA	52.3 Å²
Synonyms	(R)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride, Methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride (1:1), methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride, Methyl (R)-b-Amino-2,4,5-trifluorobenzenebutanoate HCl, Methyl (R)-beta-Amino-2,4,5-F3-benzenebutanoate HCl, (R)-Methyl3-amino-4-(2,4,5-trifluorophenyl)butanoatehydrochloride, Methyl (R)-b-Amino-2,4,5-trifluorobenzenebutanoate hydrochloride, (3R)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (R)-Sitagliptin Methyl-Ester Hydrochloride?

The CAS Registry Number of (R)-Sitagliptin Methyl-Ester Hydrochloride is 1374985-05-3. It is also known as (R)-Methyl 3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride, Methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride (1:1), methyl (3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoate hydrochloride.

What is the molecular formula and molecular weight of (R)-Sitagliptin Methyl-Ester Hydrochloride?

(R)-Sitagliptin Methyl-Ester Hydrochloride has the molecular formula C11H13ClF3NO2 and a molecular weight of 283.67 g/mol.

What is (R)-Sitagliptin Methyl-Ester Hydrochloride used for?

(R)-Sitagliptin Methyl-Ester Hydrochloride is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (R)-Sitagliptin Methyl-Ester Hydrochloride can I order?

We supply (R)-Sitagliptin Methyl-Ester Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (R)-Sitagliptin Methyl-Ester Hydrochloride?

Yes. Every lot of (R)-Sitagliptin Methyl-Ester Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (R)-Sitagliptin Methyl-Ester Hydrochloride be shipped internationally?

Yes. We export (R)-Sitagliptin Methyl-Ester Hydrochloride worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.