rac N-Desmethyl Tramadol

Name: rac N-Desmethyl Tramadol
Brand: Vaqora Chemicals
SKU: VQ-042639

About rac N-Desmethyl Tramadol

rac N-Desmethyl Tramadol (CAS 75377-45-6) is a metabolite or degradation product of Tramadol offered by Vaqora Chemicals. The compound has the formula C15H23NO2, corresponding to a molecular weight of 249.35 g/mol. Its systematic (IUPAC) name is cis-(1R,2R)-1-(3-methoxyphenyl)-2-(methylaminomethyl)cyclohexan-1-ol. Common synonyms include N-Desmethyl Tramadol and Nortramadol.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Tramadol, as well as in QC testing and ANDA/DMF documentation. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, rac N-Desmethyl Tramadol is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Tramadol

View every impurity, metabolite and intermediate we list for Tramadol.

Tramadol impurities

Specifications & identifiers

Chemical identifiers
Product name	rac N-Desmethyl Tramadol
Catalogue No.	VQ-042639
CAS Number	75377-45-6
IUPAC name	cis-(1R,2R)-1-(3-methoxyphenyl)-2-(methylaminomethyl)cyclohexan-1-ol
Molecular formula	C₁₅H₂₃NO₂
Molecular weight	249.35 g/mol
Exact mass	249.1729
Grade	Reference Standard
HSN code	38229090
InChIKey	VUMQHLSPUAFKKK-HIFRSBDPSA-N
SMILES	CNC[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O
PubChem CID	12149038

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 3
TPSA	41.5 Å²
Synonyms	N-Desmethyl Tramadol, Nortramadol, N-Desmethyltramadol, Tramadol metabolite M2, Cyclohexanol, 1-(3-methoxyphenyl)-2-((methylamino)methyl)-, (1R,2R)-rel-, (+)-N-Desmethyl Tramadol, (1R,2R)-1-(3-methoxyphenyl)-2-(methylaminomethyl)cyclohexan-1-ol, (1R,2R)-1-(3-methoxyphenyl)-2-((methylamino)methyl)cyclohexan-1-ol, Cyclohexanol, 1-(3-methoxyphenyl)-2-((methylamino)methyl)-, cis-(+/-)-

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of rac N-Desmethyl Tramadol?

The CAS Registry Number of rac N-Desmethyl Tramadol is 75377-45-6. It is also known as N-Desmethyl Tramadol, Nortramadol, N-Desmethyltramadol.

What is the molecular formula and molecular weight of rac N-Desmethyl Tramadol?

rac N-Desmethyl Tramadol has the molecular formula C15H23NO2 and a molecular weight of 249.35 g/mol. Its IUPAC name is cis-(1R,2R)-1-(3-methoxyphenyl)-2-(methylaminomethyl)cyclohexan-1-ol.

What is rac N-Desmethyl Tramadol used for?

rac N-Desmethyl Tramadol is supplied as a characterised reference material related to Tramadol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of rac N-Desmethyl Tramadol can I order?

We supply rac N-Desmethyl Tramadol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with rac N-Desmethyl Tramadol?

Yes. Every lot of rac N-Desmethyl Tramadol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can rac N-Desmethyl Tramadol be shipped internationally?

Yes. We export rac N-Desmethyl Tramadol worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.