rac threo-Dihydro Bupropion

Name: rac threo-Dihydro Bupropion
Brand: Vaqora Chemicals
SKU: VQ-028860

About rac threo-Dihydro Bupropion

Listed under CAS 92264-82-9, rac threo-Dihydro Bupropion is an impurity of Bupropion available from Vaqora Chemicals. With the molecular formula C13H20ClNO, it has a molar mass of 241.76 g/mol. Systematically, it is named (1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol. It is also known as Bupropion Dihydro (R,R)-Isomer and Enantiomer or S,S-threo-Hydrobupropion.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Bupropion, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer rac threo-Dihydro Bupropion in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Bupropion

View every impurity, metabolite and intermediate we list for Bupropion.

Bupropion impurities

Specifications & identifiers

Chemical identifiers
Product name	rac threo-Dihydro Bupropion
Catalogue No.	VQ-028860
CAS Number	92264-82-9
IUPAC name	(1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol
Molecular formula	C₁₃H₂₀ClNO
Molecular weight	241.76 g/mol
Exact mass	241.1233
Grade	Reference Standard
HSN code	38229090
InChIKey	NDPTTXIBLSWNSF-JOYOIKCWSA-N
SMILES	C[C@@H]([C@H](C1=CC(=CC=C1)Cl)O)NC(C)(C)C
PubChem CID	9834682

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	2 / 2
TPSA	32.3 Å²
Synonyms	Bupropion Dihydro (R,R)-Isomer and Enantiomer, Benzenemethanol, 3-chloro-alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)-, (alphaR)-rel-, rel-(alphaR)-3-Chloro-alpha-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol, rel-(alphaR)-3-Chloro-alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)benzenemethanol, S,S-threo-Hydrobupropion, Threohydrobupropion, (+-)-, rel-(, AR)-3-Chloro-, A-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of rac threo-Dihydro Bupropion?

The CAS Registry Number of rac threo-Dihydro Bupropion is 92264-82-9. It is also known as Bupropion Dihydro (R,R)-Isomer and Enantiomer, Benzenemethanol, 3-chloro-alpha-((1R)-1-((1,1-dimethylethyl)amino)ethyl)-, (alphaR)-rel-, rel-(alphaR)-3-Chloro-alpha-[(1R)-1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol.

What is the molecular formula and molecular weight of rac threo-Dihydro Bupropion?

rac threo-Dihydro Bupropion has the molecular formula C13H20ClNO and a molecular weight of 241.76 g/mol. Its IUPAC name is (1S,2S)-2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-ol.

What is rac threo-Dihydro Bupropion used for?

rac threo-Dihydro Bupropion is supplied as a characterised reference material related to Bupropion. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of rac threo-Dihydro Bupropion can I order?

We supply rac threo-Dihydro Bupropion in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with rac threo-Dihydro Bupropion?

Yes. Every lot of rac threo-Dihydro Bupropion is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can rac threo-Dihydro Bupropion be shipped internationally?

Yes. rac threo-Dihydro Bupropion is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.