Ranitidine Impurity B

Name: Ranitidine Impurity B
Brand: Vaqora Chemicals
SKU: VQ-005697

About Ranitidine Impurity B

Ranitidine Impurity B is an impurity of Ranitidine carrying the CAS registry number 66356-53-4. Its molecular formula is C10H18N2OS and its molecular weight is 214.33 g/mol. The IUPAC name is 2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethanamine. Alternative names: 5-ADFM and N- Hydro Ranitidine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 3 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ranitidine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Ranitidine Impurity B in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ranitidine

View every impurity, metabolite and intermediate we list for Ranitidine.

Ranitidine impurities

Specifications & identifiers

Chemical identifiers
Product name	Ranitidine Impurity B
Catalogue No.	VQ-005697
CAS Number	66356-53-4
Other CAS	100750-35-4, 91224-69-0, 72545-66-5, 256948-32-0
IUPAC name	2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethanamine
Molecular formula	C₁₀H₁₈N₂OS
Molecular weight	214.33 g/mol
Exact mass	214.114
Grade	Reference Standard
HSN code	38229090
InChIKey	JFGCGQJHMUYGLU-UHFFFAOYSA-N
SMILES	CN(C)CC1=CC=C(O1)CSCCN
PubChem CID	162203

Physical properties
Physical form	Solid
LogP (XLogP3)	-1
H-bond donors / acceptors	1 / 4
TPSA	67.7 Å²
Synonyms	5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine, 2-[[5-[(Dimethylamino)methyl]-2-furyl]methylsulfanyl]ethanamine, 2-[[(2-Aminoethyl)thio]methyl]-5-[(dimethylamino)methyl]furan, 2-{[(5-Dimethylamino)methylfurfuryl]thyo}ethylamine, 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine, 5-((2-Aminoethyl)thiomethyl)-N,N-dimethyl-2-furanmethanamine, 5-ADFM, 2-(2-Aminoethylthiomethyl)-5-dimethylaminomethylfuran, N- Hydro Ranitidine, 2-((2-Aminoethylthio)methyl)-5-((N,N-dimethylamino)methyl)furan, 2-[({5-[(dimethylamino)methyl]-2-furyl}methyl)thio]ethan-1-amine, 2-Furanmethanamine, 5-[[(2-aminoethyl)thio]methyl]-N,N-dimethyl-

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation

Precautionary statements: P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P319, P321, P333 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ranitidine Impurity B?

The CAS Registry Number of Ranitidine Impurity B is 66356-53-4. It is also known as 5-[[(2-Aminoethyl)thio]methyl]-N,N-dimethyl-2-furanmethanamine, 2-[[5-[(Dimethylamino)methyl]-2-furyl]methylsulfanyl]ethanamine, 2-[[(2-Aminoethyl)thio]methyl]-5-[(dimethylamino)methyl]furan.

What is the molecular formula and molecular weight of Ranitidine Impurity B?

Ranitidine Impurity B has the molecular formula C10H18N2OS and a molecular weight of 214.33 g/mol. Its IUPAC name is 2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethanamine.

What is Ranitidine Impurity B used for?

Ranitidine Impurity B is supplied as a characterised reference material related to Ranitidine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ranitidine Impurity B can I order?

We supply Ranitidine Impurity B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ranitidine Impurity B?

Yes. Every lot of Ranitidine Impurity B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ranitidine Impurity B be shipped internationally?

Yes. Ranitidine Impurity B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.