Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropy… 1355024-07-5

Name: Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one
Brand: Vaqora Chemicals
SKU: VQ-042094

About Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one

Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one is a nitrosamine impurity of Sapropterin carrying the CAS registry number 1355024-07-5. Formula C9H14N6O4, molecular weight 270.25 g/mol. Systematically, it is named (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5-nitroso-3,6,7,8-tetrahydropteridin-4-one. Common synonyms include N-nitroso-sapropterin-2.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Sapropterin, method validation (AMV) and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Sapropterin

View every impurity, metabolite and intermediate we list for Sapropterin.

Sapropterin impurities

Specifications & identifiers

Chemical identifiers
Product name	Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one
Catalogue No.	VQ-042094
CAS Number	1355024-07-5
IUPAC name	(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5-nitroso-3,6,7,8-tetrahydropteridin-4-one
Molecular formula	C₉H₁₄N₆O₄
Molecular weight	270.25 g/mol
Exact mass	270.1077
Grade	Reference Standard
HSN code	38229090
InChIKey	JNWSZKUCTRQPEM-RPDRRWSUSA-N
SMILES	C[C@@H]([C@@H]([C@H]1CNC2=C(N1N=O)C(=O)NC(=N2)N)O)O
PubChem CID	172866420

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.1
H-bond donors / acceptors	5 / 8
TPSA	153 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one?

The CAS Registry Number of Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one is 1355024-07-5. It is also known as N-nitroso-sapropterin-2, (R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(1H)-one.

What is the molecular formula and molecular weight of Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one?

Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one has the molecular formula C9H14N6O4 and a molecular weight of 270.25 g/mol. Its IUPAC name is (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5-nitroso-3,6,7,8-tetrahydropteridin-4-one.

What is Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one used for?

Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one is supplied as a characterised reference material related to Sapropterin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one can I order?

We supply Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one?

Yes. Every lot of Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one be shipped internationally?

Yes. We export Rel-(R)-2-Amino-6-((1R,2S)-1,2-dihydroxypropyl)-5-nitroso-5,6,7,8-tetrahydropteridin-4(3H)-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.