Remdesivir O-Desphosphate Analogue

Name: Remdesivir O-Desphosphate Analogue
Brand: Vaqora Chemicals
SKU: VQ-005749

About Remdesivir O-Desphosphate Analogue

Remdesivir O-Desphosphate Analogue (CAS 1191237-69-0) is an impurity of Remdesivir offered by Vaqora Chemicals. Its molecular formula is C12H13N5O4 and its molecular weight is 291.26 g/mol. It is also known as Tri Hydroxy Nitrile Remdesivir or EVO-984.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Remdesivir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Remdesivir O-Desphosphate Analogue is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Remdesivir

View every impurity, metabolite and intermediate we list for Remdesivir.

Remdesivir impurities

Specifications & identifiers

Chemical identifiers
Product name	Remdesivir O-Desphosphate Analogue
Catalogue No.	VQ-005749
CAS Number	1191237-69-0
IUPAC name	(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
Molecular formula	C₁₂H₁₃N₅O₄
Molecular weight	291.26 g/mol
Exact mass	291.0968
Grade	Reference Standard
HSN code	38229090
InChIKey	BRDWIEOJOWJCLU-LTGWCKQJSA-N
SMILES	C1=C2C(=NC=NN2C(=C1)[C@]3([C@@H]([C@@H]([C@H](O3)CO)O)O)C#N)N
PubChem CID	44468216

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.4
H-bond donors / acceptors	4 / 8
TPSA	150 Å²
Synonyms	2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile, Tri Hydroxy Nitrile Remdesivir, EVO-984, 2-C-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile, D-Altrononitrile, 2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-, EVO 984, reacted form, Nucleoside of Remdesivir, EX-A3056, Remdesivir metabolite(GS-441524), Remdesivir metabolite(GS-441524)?, Remdesivir intermediate(GS-441524)

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child
H371May cause damage to organs

Precautionary statements: P203, P233, P260, P261, P264, P264 + P265, P270, P271, P272, P280, P284, P302 + P352, P304 + P340, P305 + P354 + P338, P308 + P316, P317, P318, P319, P321, P332 + P317, P333 + P317, P342 + P316, P362 + P364, P403

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Remdesivir O-Desphosphate Analogue?

The CAS Registry Number of Remdesivir O-Desphosphate Analogue is 1191237-69-0. It is also known as 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile, Tri Hydroxy Nitrile Remdesivir, EVO-984.

What is the molecular formula and molecular weight of Remdesivir O-Desphosphate Analogue?

Remdesivir O-Desphosphate Analogue has the molecular formula C12H13N5O4 and a molecular weight of 291.26 g/mol. Its IUPAC name is (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile.

What is Remdesivir O-Desphosphate Analogue used for?

Remdesivir O-Desphosphate Analogue is supplied as a characterised reference material related to Remdesivir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Remdesivir O-Desphosphate Analogue can I order?

We supply Remdesivir O-Desphosphate Analogue in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Remdesivir O-Desphosphate Analogue?

Yes. Every lot of Remdesivir O-Desphosphate Analogue is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Remdesivir O-Desphosphate Analogue be shipped internationally?

Yes. Remdesivir O-Desphosphate Analogue is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.