Rifampicin N-oxide

Name: Rifampicin N-oxide
Brand: Vaqora Chemicals
SKU: VQ-041902

About Rifampicin N-oxide

Listed under CAS 51963-55-4, Rifampicin N-oxide is a metabolite or degradation product of Rifaximin available from Vaqora Chemicals. With the molecular formula C43H58N4O13, it has a molar mass of 838.9 g/mol. Common synonyms include Rifaximin Imine-N-Oxide and Rifaximin N-Oxide.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 8 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Rifaximin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rifampicin N-oxide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Rifaximin

View every impurity, metabolite and intermediate we list for Rifaximin.

Rifaximin impurities

Specifications & identifiers

Chemical identifiers
Product name	Rifampicin N-oxide
Catalogue No.	VQ-041902
CAS Number	51963-55-4
IUPAC name	[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-(4-methyl-4-oxidopiperazin-4-ium-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate
Molecular formula	C₄₃H₅₈N₄O₁₃
Molecular weight	838.9 g/mol
Exact mass	838.4
Grade	Reference Standard
HSN code	38229090
InChIKey	HLBLHKPXLRRUNR-WLSIYKJHSA-N
SMILES	C[C@H]1/C=C/C=C(\C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)/C=N/N5CC[N+](CC5)(C)[O-])/C
PubChem CID	137231149

Physical properties
Physical form	Solid
LogP (XLogP3)	4.4
H-bond donors / acceptors	6 / 15
TPSA	235 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P261, P263, P264, P264 + P265, P270, P271, P272, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P333 + P317, P337 + P317, P362 + P364, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rifampicin N-oxide?

The CAS Registry Number of Rifampicin N-oxide is 51963-55-4. It is also known as Rifaximin Imine-N-Oxide, Rifaximin N-Oxide, Rifamycin, 3-[[(4-methyl-4-oxido-1-piperazinyl)imino]methyl]-.

What is the molecular formula and molecular weight of Rifampicin N-oxide?

Rifampicin N-oxide has the molecular formula C43H58N4O13 and a molecular weight of 838.9 g/mol.

What is Rifampicin N-oxide used for?

Rifampicin N-oxide is supplied as a characterised reference material related to Rifaximin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rifampicin N-oxide can I order?

We supply Rifampicin N-oxide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rifampicin N-oxide?

Yes. Every lot of Rifampicin N-oxide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rifampicin N-oxide be shipped internationally?

Yes. Rifampicin N-oxide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.