Ripretinib

Name: Ripretinib
Brand: Vaqora Chemicals
SKU: VQ-027832

About Ripretinib

Ripretinib is a high-purity reference standard of Ripretinib carrying the CAS registry number 1442472-39-0. The compound has the formula C24H21BrFN5O2, corresponding to a molecular weight of 510.4 g/mol. The IUPAC name is 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea. Common synonyms include KIT/PDGFR Inhibitor DCC-2618 and DCC-2618.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Ripretinib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Ripretinib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Ripretinib

View every impurity, metabolite and intermediate we list for Ripretinib.

Ripretinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Ripretinib
Catalogue No.	VQ-027832
CAS Number	1442472-39-0
IUPAC name	1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea
Molecular formula	C₂₄H₂₁BrFN₅O₂
Molecular weight	510.4 g/mol
Exact mass	509.0863
Grade	Reference Standard
HSN code	38229090
InChIKey	CEFJVGZHQAGLHS-UHFFFAOYSA-N
SMILES	CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NC
PubChem CID	71584930

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	3 / 5
TPSA	86.4 Å²
Synonyms	KIT/PDGFR Inhibitor DCC-2618, DCC-2618, Ripretinib free base, Ripretinib (DCC-2618), Ripretinib (JAN/USAN), DCC-26, EX-A4883

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ripretinib?

The CAS Registry Number of Ripretinib is 1442472-39-0. It is also known as KIT/PDGFR Inhibitor DCC-2618, DCC-2618, Ripretinib free base.

What is the molecular formula and molecular weight of Ripretinib?

Ripretinib has the molecular formula C24H21BrFN5O2 and a molecular weight of 510.4 g/mol. Its IUPAC name is 1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea.

What is Ripretinib used for?

Ripretinib is supplied as a characterised reference material related to Ripretinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ripretinib can I order?

We supply Ripretinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ripretinib?

Yes. Every lot of Ripretinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ripretinib be shipped internationally?

Yes. We export Ripretinib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.