Roxadustat

Name: Roxadustat
Brand: Vaqora Chemicals
SKU: VQ-007732

About Roxadustat

Listed under CAS 808118-40-3, Roxadustat is a high-purity reference standard of Roxadustat available from Vaqora Chemicals. With the molecular formula C19H16N2O5, it has a molar mass of 352.3 g/mol. The IUPAC name is 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid. Common synonyms include ASP 1517 and ASP-1517.

The product is provided as a powder. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Roxadustat, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Roxadustat

View every impurity, metabolite and intermediate we list for Roxadustat.

Roxadustat impurities

Specifications & identifiers

Chemical identifiers
Product name	Roxadustat
Catalogue No.	VQ-007732
CAS Number	808118-40-3
IUPAC name	2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
Molecular formula	C₁₉H₁₆N₂O₅
Molecular weight	352.3 g/mol
Exact mass	352.1059
Grade	Reference Standard
HSN code	38229090
InChIKey	YOZBGTLTNGAVFU-UHFFFAOYSA-N
SMILES	CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3
PubChem CID	11256664

Physical properties
Physical form	Powder
LogP (XLogP3)	3.4
H-bond donors / acceptors	3 / 6
TPSA	109 Å²
Synonyms	N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, (4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine, [(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine, 2-(4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetic acid, [[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid, ASP 1517, ASP-1517, (((4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl)amino)acetic acid, N-[(4-hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine, 2-((4-hydroxy-1-methyl-7-(phenoxy)isoquinoline-3-carbonyl)amino)acetic acid, 2-[[4-hydroxy-1-methyl-7-(phenoxy)isoquinoline-3-carbonyl]amino]acetic acid, Roxadustat (FG-4592)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Roxadustat?

The CAS Registry Number of Roxadustat is 808118-40-3. It is also known as N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine, (4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine, [(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]glycine.

What is the molecular formula and molecular weight of Roxadustat?

Roxadustat has the molecular formula C19H16N2O5 and a molecular weight of 352.3 g/mol. Its IUPAC name is 2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid.

What is Roxadustat used for?

Roxadustat is supplied as a characterised reference material related to Roxadustat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Roxadustat can I order?

We supply Roxadustat in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Roxadustat?

Yes. Every lot of Roxadustat is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Roxadustat be shipped internationally?

Yes. Roxadustat is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.