(S)-(-)-2-Acetoxypropionyl Chloride

Name: (S)-(-)-2-Acetoxypropionyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-032539

About (S)-(-)-2-Acetoxypropionyl Chloride

(S)-(-)-2-Acetoxypropionyl Chloride is an impurity of Vancomycin carrying the CAS registry number 36394-75-9. The compound has the formula C5H7ClO3, corresponding to a molecular weight of 150.56 g/mol. The IUPAC name is [(2S)-1-chloro-1-oxopropan-2-yl] acetate. Common synonyms include (1S)-2-chloro-1-methyl-2-oxoethyl acetate and (2S)-(-)-2-Acetoxypropanoyl chloride.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Vancomycin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer (S)-(-)-2-Acetoxypropionyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vancomycin

View every impurity, metabolite and intermediate we list for Vancomycin.

Vancomycin impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-(-)-2-Acetoxypropionyl Chloride
Catalogue No.	VQ-032539
CAS Number	36394-75-9
IUPAC name	[(2S)-1-chloro-1-oxopropan-2-yl] acetate
Molecular formula	C₅H₇ClO₃
Molecular weight	150.56 g/mol
Exact mass	150.0084
Grade	Reference Standard
HSN code	38229090
InChIKey	ALHZEIINTQJLOT-VKHMYHEASA-N
SMILES	C[C@@H](C(=O)Cl)OC(=O)C
PubChem CID	11094804

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	0 / 3
TPSA	43.4 Å²
Synonyms	(1S)-2-chloro-1-methyl-2-oxoethyl acetate, (2S)-(-)-2-Acetoxypropanoyl chloride, (2S)-1-chloro-1-oxopropan-2-yl acetate, 2(S)-acetoxypropionyl chloride, (S)-1-chloro-1-oxopropan-2-yl acetate, L-a-Acetoxypropionyl Chloride, (S)-2-acetoxypropanyl chloride, (R)-(-)-2-mandelic acid, acetic acid (S)-1-chlorocarbony, L-alpha-Acetoxypropionyl Chloride

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction

Precautionary statements: P260, P261, P264, P270, P272, P280, P301 + P317, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P330, P333 + P317, P362 + P364, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-(-)-2-Acetoxypropionyl Chloride?

The CAS Registry Number of (S)-(-)-2-Acetoxypropionyl Chloride is 36394-75-9. It is also known as (1S)-2-chloro-1-methyl-2-oxoethyl acetate, (2S)-(-)-2-Acetoxypropanoyl chloride, (2S)-1-chloro-1-oxopropan-2-yl acetate.

What is the molecular formula and molecular weight of (S)-(-)-2-Acetoxypropionyl Chloride?

(S)-(-)-2-Acetoxypropionyl Chloride has the molecular formula C5H7ClO3 and a molecular weight of 150.56 g/mol. Its IUPAC name is [(2S)-1-chloro-1-oxopropan-2-yl] acetate.

What is (S)-(-)-2-Acetoxypropionyl Chloride used for?

(S)-(-)-2-Acetoxypropionyl Chloride is supplied as a characterised reference material related to Vancomycin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-(-)-2-Acetoxypropionyl Chloride can I order?

We supply (S)-(-)-2-Acetoxypropionyl Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-(-)-2-Acetoxypropionyl Chloride?

Yes. Every lot of (S)-(-)-2-Acetoxypropionyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-(-)-2-Acetoxypropionyl Chloride be shipped internationally?

Yes. (S)-(-)-2-Acetoxypropionyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.