(S)-2-Amino-2-(2-chlorophenyl)acetic Acid

Name: (S)-2-Amino-2-(2-chlorophenyl)acetic Acid
Brand: Vaqora Chemicals
SKU: VQ-040728

About (S)-2-Amino-2-(2-chlorophenyl)acetic Acid

(S)-2-Amino-2-(2-chlorophenyl)acetic Acid (CAS 141315-50-6) is a process intermediate or related compound of Tretinoin offered by Vaqora Chemicals. Formula C8H8ClNO2, molecular weight 185.61 g/mol. Its systematic (IUPAC) name is (2S)-2-amino-2-(2-chlorophenyl)acetic acid. Alternative names: L-2-Chlorophenylglycine and L-(2-Chlorophenyl)glycine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Tretinoin, tracking process-related impurities and validating analytical methods. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Tretinoin

View every impurity, metabolite and intermediate we list for Tretinoin.

Tretinoin impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-2-Amino-2-(2-chlorophenyl)acetic Acid
Catalogue No.	VQ-040728
CAS Number	141315-50-6
IUPAC name	(2S)-2-amino-2-(2-chlorophenyl)acetic acid
Molecular formula	C₈H₈ClNO₂
Molecular weight	185.61 g/mol
Exact mass	185.0244
HSN code	2933
InChIKey	LMIZLNPFTRQPSF-ZETCQYMHSA-N
SMILES	C1=CC=C(C(=C1)[C@@H](C(=O)O)N)Cl
PubChem CID	1501937

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.1
H-bond donors / acceptors	2 / 3
TPSA	63.3 Å²
Synonyms	(alphaS)-alpha-Amino-2-chlorobenzeneacetic acid, L-2-Chlorophenylglycine, L-(2-Chlorophenyl)glycine, L-(+)-2-Chlorophenylglycine, (s)-(+)-2-chlorophenylglycine, L-(+)-(2-Chlorophenyl)glycine, L-(+)-2-(2-Chlorophenyl)glycine, (S)-Amino-(2-Chloro-Phenyl)-Acetic Acid, (S)-2-Chorophenylglycine, (s)-2-chlorophenylglycine, 2-Chlorophenylglycine, L-, 2-Chloro-L-(+)-2-phenylglycine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P261, P264, P264 + P265, P271, P273, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-2-Amino-2-(2-chlorophenyl)acetic Acid?

The CAS Registry Number of (S)-2-Amino-2-(2-chlorophenyl)acetic Acid is 141315-50-6. It is also known as (alphaS)-alpha-Amino-2-chlorobenzeneacetic acid, L-2-Chlorophenylglycine, L-(2-Chlorophenyl)glycine.

What is the molecular formula and molecular weight of (S)-2-Amino-2-(2-chlorophenyl)acetic Acid?

(S)-2-Amino-2-(2-chlorophenyl)acetic Acid has the molecular formula C8H8ClNO2 and a molecular weight of 185.61 g/mol. Its IUPAC name is (2S)-2-amino-2-(2-chlorophenyl)acetic acid.

What is (S)-2-Amino-2-(2-chlorophenyl)acetic Acid used for?

(S)-2-Amino-2-(2-chlorophenyl)acetic Acid is supplied as a characterised reference material related to Tretinoin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-2-Amino-2-(2-chlorophenyl)acetic Acid can I order?

We supply (S)-2-Amino-2-(2-chlorophenyl)acetic Acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-2-Amino-2-(2-chlorophenyl)acetic Acid?

Yes. Every lot of (S)-2-Amino-2-(2-chlorophenyl)acetic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-2-Amino-2-(2-chlorophenyl)acetic Acid be shipped internationally?

Yes. (S)-2-Amino-2-(2-chlorophenyl)acetic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.