(S)-3-Methylpiperazin-2-one

Name: (S)-3-Methylpiperazin-2-one
Brand: Vaqora Chemicals
SKU: VQ-032870

About (S)-3-Methylpiperazin-2-one

(S)-3-Methylpiperazin-2-one is an impurity of Fezolinetant carrying the CAS registry number 78551-38-9. With the molecular formula C5H10N2O, it has a molar mass of 114.15 g/mol. Its systematic (IUPAC) name is (3S)-3-methylpiperazin-2-one. Alternative names: (S)-3-Methyl-2-ketopiperazine and 2-Piperazinone,3-methyl-, (3S)-.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Fezolinetant, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Fezolinetant

View every impurity, metabolite and intermediate we list for Fezolinetant.

Fezolinetant impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-3-Methylpiperazin-2-one
Catalogue No.	VQ-032870
CAS Number	78551-38-9
IUPAC name	(3S)-3-methylpiperazin-2-one
Molecular formula	C₅H₁₀N₂O
Molecular weight	114.15 g/mol
Exact mass	114.0793
Grade	Reference Standard
HSN code	38229090
InChIKey	BSPUWRUTIOUGMZ-BYPYZUCNSA-N
SMILES	C[C@H]1C(=O)NCCN1
PubChem CID	13190462

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.7
H-bond donors / acceptors	2 / 2
TPSA	41.1 Å²

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P264 + P265, P271, P280, P284, P304 + P340, P305 + P351 + P338, P337 + P317, P342 + P316, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-3-Methylpiperazin-2-one?

The CAS Registry Number of (S)-3-Methylpiperazin-2-one is 78551-38-9. It is also known as (S)-3-Methyl-2-ketopiperazine, 2-Piperazinone,3-methyl-, (3S)-, (3S)-3-methyl-2-piperazinone.

What is the molecular formula and molecular weight of (S)-3-Methylpiperazin-2-one?

(S)-3-Methylpiperazin-2-one has the molecular formula C5H10N2O and a molecular weight of 114.15 g/mol. Its IUPAC name is (3S)-3-methylpiperazin-2-one.

What is (S)-3-Methylpiperazin-2-one used for?

(S)-3-Methylpiperazin-2-one is supplied as a characterised reference material related to Fezolinetant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-3-Methylpiperazin-2-one can I order?

We supply (S)-3-Methylpiperazin-2-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-3-Methylpiperazin-2-one?

Yes. Every lot of (S)-3-Methylpiperazin-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-3-Methylpiperazin-2-one be shipped internationally?

Yes. (S)-3-Methylpiperazin-2-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.