(S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione
(S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (CAS 2487573-05-5) – Apremilast impurity standard. COA included.
About (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione
Listed under CAS 2487573-05-5, (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is a metabolite or degradation product of Apremilast available from Vaqora Chemicals. Formula C18H18N2O6S, molecular weight 390.4 g/mol. Systematically, it is named 4-amino-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione.
It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.
Analytical teams use this compound to identify metabolites and degradants of Apremilast, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is dispatched with a Certificate of Analysis (COA) to destinations worldwide.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Industries
View every impurity, metabolite and intermediate we list for Apremilast.
Apremilast impuritiesSpecifications & identifiers
| Product name | (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione |
|---|---|
| Catalogue No. | VQ-035268 |
| CAS Number | 2487573-05-5 |
| IUPAC name | 4-amino-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione |
| Molecular formula | C18H18N2O6S |
| Molecular weight | 390.4 g/mol |
| Exact mass | 390.0886 |
| Grade | Reference Standard |
| HSN code | 38229090 |
| InChIKey | XCFPVUKMYSBJCB-CYBMUJFWSA-N |
| SMILES | COC1=C(C=C(C=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=C(C2=O)C(=CC=C3)N)O |
| PubChem CID | 178343701 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.3 |
| H-bond donors / acceptors | 2 / 7 |
| TPSA | 135 Ų |
Documents
Frequently asked questions
What is the CAS number of (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione?
The CAS Registry Number of (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is 2487573-05-5.
What is the molecular formula and molecular weight of (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione?
(S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione has the molecular formula C18H18N2O6S and a molecular weight of 390.4 g/mol. Its IUPAC name is 4-amino-2-[(1S)-1-(3-hydroxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindole-1,3-dione.
What is (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione used for?
(S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is supplied as a characterised reference material related to Apremilast. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione can I order?
We supply (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione?
Yes. Every lot of (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione be shipped internationally?
Yes. We export (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.
Enquire about (S)-4-Amino-2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione
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