(S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)… 376348-77-5

Name: (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide
Brand: Vaqora Chemicals
SKU: VQ-026560

About (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide

(S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide (CAS 376348-77-5) is a metabolite or degradation product of Maraviroc offered by Vaqora Chemicals. Formula C16H21F2NO2, molecular weight 297.34 g/mol. Its systematic (IUPAC) name is 4,4-difluoro-N-[(1S)-3-hydroxy-1-phenylpropyl]cyclohexane-1-carboxamide.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Maraviroc, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Maraviroc

View every impurity, metabolite and intermediate we list for Maraviroc.

Maraviroc impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide
Catalogue No.	VQ-026560
CAS Number	376348-77-5
IUPAC name	4,4-difluoro-N-[(1S)-3-hydroxy-1-phenylpropyl]cyclohexane-1-carboxamide
Molecular formula	C₁₆H₂₁F₂NO₂
Molecular weight	297.34 g/mol
Exact mass	297.154
Grade	Reference Standard
HSN code	38229090
InChIKey	OOIJZFMUKIGIRX-AWEZNQCLSA-N
SMILES	C1CC(CCC1C(=O)N[C@@H](CCO)C2=CC=CC=C2)(F)F
PubChem CID	9814730

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 4
TPSA	49.3 Å²
Synonyms	4,4-Difluoro-N-((1S)-3-hydroxy-1-phenylpropyl)cyclohexanecarboxamide, 4,4-difluoro-n-[(1S)-3-hydroxy-1-phenylpropyl]cyclohexanecarboxamide, (S)-4,4-difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexanecarboxamide, 4,4-Difluoro-N-[(1S)-3-hydroxy-1-phenylpropyl]-cyclohexanecarboxamide, Cyclohexanecarboxamide, 4,4-difluoro-N-[(1S)-3-hydroxy-1-phenylpropyl]-, (s)-3-phenyl-3-(4,4-difluorocyclohexylcarbonylamino)propanol, 4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboximidic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide?

The CAS Registry Number of (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide is 376348-77-5. It is also known as 4,4-Difluoro-N-((1S)-3-hydroxy-1-phenylpropyl)cyclohexanecarboxamide, 4,4-difluoro-n-[(1S)-3-hydroxy-1-phenylpropyl]cyclohexanecarboxamide, (S)-4,4-difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexanecarboxamide.

What is the molecular formula and molecular weight of (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide?

(S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide has the molecular formula C16H21F2NO2 and a molecular weight of 297.34 g/mol. Its IUPAC name is 4,4-difluoro-N-[(1S)-3-hydroxy-1-phenylpropyl]cyclohexane-1-carboxamide.

What is (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide used for?

(S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide is supplied as a characterised reference material related to Maraviroc. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide can I order?

We supply (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide?

Yes. Every lot of (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide be shipped internationally?

Yes. (S)-4,4-Difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.