(S)-Naproxen Acyl-beta-D-glucuronide

Name: (S)-Naproxen Acyl-beta-D-glucuronide
Brand: Vaqora Chemicals
SKU: VQ-032067

About (S)-Naproxen Acyl-beta-D-glucuronide

Vaqora Chemicals supplies (S)-Naproxen Acyl-beta-D-glucuronide, a metabolite or degradation product of Naproxen registered under CAS number 41945-43-1. With the molecular formula C20H22O9, it has a molar mass of 406.4 g/mol. The IUPAC name is (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxyoxane-2-carboxylic acid. Alternative names: Naproxen Glucuronide and (S)-Naproxen Acyl-β-D-glucuronide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Analytical teams use this compound to identify metabolites and degradants of Naproxen, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, (S)-Naproxen Acyl-beta-D-glucuronide is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Naproxen

View every impurity, metabolite and intermediate we list for Naproxen.

Naproxen impurities

Specifications & identifiers

Chemical identifiers
Product name	(S)-Naproxen Acyl-beta-D-glucuronide
Catalogue No.	VQ-032067
CAS Number	41945-43-1
IUPAC name	(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxyoxane-2-carboxylic acid
Molecular formula	C₂₀H₂₂O₉
Molecular weight	406.4 g/mol
Exact mass	406.1264
Grade	Reference Standard
HSN code	38229090
InChIKey	XRHIELLXTVJOKM-ODXKUVGNSA-N
SMILES	C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O
PubChem CID	181715

Physical properties
Physical form	Solid
LogP (XLogP3)	1.6
H-bond donors / acceptors	4 / 9
TPSA	143 Å²
Synonyms	Naproxen Glucuronide, (S)-Naproxen Acyl-β-D-glucuronide, Naproxen Acyl-β-D-glucuronide, Naproxen glucuronide, (S)-, (S)-Naproxen-beta-D-glucuronide, (S)-Naproxen Glucuronide, 1-[(a-S)-6-Methoxy-a-methyl-2-naphthaleneacetate], 1-O-[2-(6-Methoxynaphthalen-2-yl)propanoyl]hexopyranuronic acid, 1-O-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]-beta-D-glucopyranuronic acid, beta-D-Glucopyranuronic acid, 1-(6-methoxy-alpha-methyl-2-naphthaleneacetate), (S)-, beta-D-Glucopyranuronic acid, 1-[(alphaS)-6-methoxy-alpha-methyl-2-naphthaleneacetate]

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (S)-Naproxen Acyl-beta-D-glucuronide?

The CAS Registry Number of (S)-Naproxen Acyl-beta-D-glucuronide is 41945-43-1. It is also known as Naproxen Glucuronide, (S)-Naproxen Acyl-β-D-glucuronide, Naproxen Acyl-β-D-glucuronide.

What is the molecular formula and molecular weight of (S)-Naproxen Acyl-beta-D-glucuronide?

(S)-Naproxen Acyl-beta-D-glucuronide has the molecular formula C20H22O9 and a molecular weight of 406.4 g/mol. Its IUPAC name is (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxyoxane-2-carboxylic acid.

What is (S)-Naproxen Acyl-beta-D-glucuronide used for?

(S)-Naproxen Acyl-beta-D-glucuronide is supplied as a characterised reference material related to Naproxen. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (S)-Naproxen Acyl-beta-D-glucuronide can I order?

We supply (S)-Naproxen Acyl-beta-D-glucuronide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (S)-Naproxen Acyl-beta-D-glucuronide?

Yes. Every lot of (S)-Naproxen Acyl-beta-D-glucuronide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (S)-Naproxen Acyl-beta-D-glucuronide be shipped internationally?

Yes. (S)-Naproxen Acyl-beta-D-glucuronide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.