S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-p… 132335-44-5

Name: S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine
Brand: Vaqora Chemicals
SKU: VQ-025441

About S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine

Listed under CAS 132335-44-5, S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine is an impurity of Duloxetine available from Vaqora Chemicals. With the molecular formula C9H15NOS, it has a molar mass of 185.29 g/mol. Its systematic (IUPAC) name is (1S)-3-(dimethylamino)-1-thiophen-2-ylpropan-1-ol. Alternative names: (S)-3-dimethylamino-1-(2-thienyl)-1-propanol and (s)-3-(dimethylamino)-1-(thienyl)-propan-1-ol.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Duloxetine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Duloxetine

View every impurity, metabolite and intermediate we list for Duloxetine.

Duloxetine impurities

Specifications & identifiers

Chemical identifiers
Product name	S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine
Catalogue No.	VQ-025441
CAS Number	132335-44-5
IUPAC name	(1S)-3-(dimethylamino)-1-thiophen-2-ylpropan-1-ol
Molecular formula	C₉H₁₅NOS
Molecular weight	185.29 g/mol
Exact mass	185.0874
Grade	Reference Standard
HSN code	38229090
InChIKey	XWCNSHMHUZCRLN-QMMMGPOBSA-N
SMILES	CN(C)CC[C@@H](C1=CC=CS1)O
PubChem CID	9964277

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 3
TPSA	51.7 Å²
Synonyms	(1S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine, (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol, S-(-)-N,N-Dimethyl-3-Hydroxy-3-(2-Thienyl)Propanamine, (S)-n,n-dimethyl-3-hydroxy-3-(2-thienyl)propanamine, (S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol, (S)-1-b-Hydroxy-1-(2-thienyl)-3-dimethylaminopropane, (S)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propylamine, (alphaS)-alpha-[2-(Dimethylamino)ethyl]-2-thiophenemethanol, (S)-3-dimethylamino-1-(2-thienyl)-1-propanol, (s)-3-(dimethylamino)-1-(thienyl)-propan-1-ol

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine?

The CAS Registry Number of S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine is 132335-44-5. It is also known as (1S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine, (S)-3-(Dimethylamino)-1-(2-thienyl)-1-propanol.

What is the molecular formula and molecular weight of S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine?

S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine has the molecular formula C9H15NOS and a molecular weight of 185.29 g/mol. Its IUPAC name is (1S)-3-(dimethylamino)-1-thiophen-2-ylpropan-1-ol.

What is S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine used for?

S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine is supplied as a characterised reference material related to Duloxetine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine can I order?

We supply S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine?

Yes. Every lot of S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine be shipped internationally?

Yes. S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.