Selinexor

Name: Selinexor
Brand: Vaqora Chemicals
SKU: VQ-027269

About Selinexor

Vaqora Chemicals supplies Selinexor, a high-purity reference standard of Selinexor registered under CAS number 1393477-72-9. The compound has the formula C17H11F6N7O, corresponding to a molecular weight of 443.3 g/mol. Its systematic (IUPAC) name is (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide. Alternative names: KPT-330 and ATG-010.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Selinexor, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Selinexor

View every impurity, metabolite and intermediate we list for Selinexor.

Selinexor impurities

Specifications & identifiers

Chemical identifiers
Product name	Selinexor
Catalogue No.	VQ-027269
CAS Number	1393477-72-9
IUPAC name	(Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide
Molecular formula	C₁₇H₁₁F₆N₇O
Molecular weight	443.3 g/mol
Exact mass	443.0929
Grade	Reference Standard
HSN code	38229090
InChIKey	DEVSOMFAQLZNKR-RJRFIUFISA-N
SMILES	C1=CN=C(C=N1)NNC(=O)/C=C\N2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
PubChem CID	71481097

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	2 / 12
TPSA	97.6 Å²
Synonyms	KPT-330, ATG-010, CRM1 Nuclear Export Inhibitor KPT-330, Selective Inhibitor of Nuclear Export KPT-330, Selinexor (KPT-330), KPT 330, Selinexor free base, EX-A870, compound 70 [WO2013019561A1]

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Selinexor?

The CAS Registry Number of Selinexor is 1393477-72-9. It is also known as KPT-330, ATG-010, CRM1 Nuclear Export Inhibitor KPT-330.

What is the molecular formula and molecular weight of Selinexor?

Selinexor has the molecular formula C17H11F6N7O and a molecular weight of 443.3 g/mol. Its IUPAC name is (Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide.

What is Selinexor used for?

Selinexor is supplied as a characterised reference material related to Selinexor. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Selinexor can I order?

We supply Selinexor in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Selinexor?

Yes. Every lot of Selinexor is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Selinexor be shipped internationally?

Yes. Selinexor is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.