Sennoside B

Name: Sennoside B
Brand: Vaqora Chemicals
SKU: VQ-033816

About Sennoside B

Sennoside B is an impurity of Sennoside carrying the CAS registry number 128-57-4. The compound has the formula C42H38O20, corresponding to a molecular weight of 862.7 g/mol. Alternative names: Sennoside B (6CI,7CI,8CI) and EX-A4953.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Sennoside to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sennoside B in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sennoside

View every impurity, metabolite and intermediate we list for Sennoside.

Sennoside impurities

Specifications & identifiers

Chemical identifiers
Product name	Sennoside B
Catalogue No.	VQ-033816
CAS Number	128-57-4
IUPAC name	(9S)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid
Molecular formula	C₄₂H₃₈O₂₀
Molecular weight	862.7 g/mol
Exact mass	862.1956
Grade	Reference Standard
HSN code	38229090
InChIKey	IPQVTOJGNYVQEO-AIFLABODSA-N
SMILES	C1=CC2=C(C(=C1)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)C(=O)C4=C([C@@H]2[C@H]5C6=C(C(=CC=C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O
PubChem CID	91440

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	12 / 20
TPSA	348 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements: P233, P260, P261, P264, P270, P271, P272, P280, P284, P301 + P317, P302 + P352, P304 + P340, P321, P330, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sennoside B?

The CAS Registry Number of Sennoside B is 128-57-4. It is also known as Sennoside B (6CI,7CI,8CI), EX-A4953, N,N-dimethyl-4-[(E,3Z)-3-(2-nitro-9-fluorenylidene)prop-1-enyl]aniline.

What is the molecular formula and molecular weight of Sennoside B?

Sennoside B has the molecular formula C42H38O20 and a molecular weight of 862.7 g/mol.

What is Sennoside B used for?

Sennoside B is supplied as a characterised reference material related to Sennoside. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sennoside B can I order?

We supply Sennoside B in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sennoside B?

Yes. Every lot of Sennoside B is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sennoside B be shipped internationally?

Yes. Sennoside B is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.