Sildenafil Chlorosulfone Impurity

Name: Sildenafil Chlorosulfone Impurity
Brand: Vaqora Chemicals
SKU: VQ-023748

About Sildenafil Chlorosulfone Impurity

Sildenafil Chlorosulfone Impurity (CAS 139756-22-2) is an impurity of Sildenafil offered by Vaqora Chemicals. Formula C17H19ClN4O4S, molecular weight 410.9 g/mol. Its systematic (IUPAC) name is 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonyl chloride. Common synonyms include Sildenafil Chlorosulfonyl Impurity and Sildenafil Chlorosulfone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Pharmaceutical QC and development laboratories use this impurity standard of Sildenafil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sildenafil Chlorosulfone Impurity is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sildenafil

View every impurity, metabolite and intermediate we list for Sildenafil.

Sildenafil impurities

Specifications & identifiers

Chemical identifiers
Product name	Sildenafil Chlorosulfone Impurity
Catalogue No.	VQ-023748
CAS Number	139756-22-2
IUPAC name	4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonyl chloride
Molecular formula	C₁₇H₁₉ClN₄O₄S
Molecular weight	410.9 g/mol
Exact mass	410.0816
Grade	Reference Standard
HSN code	38229090
InChIKey	RVVOSOSBFSYZDM-UHFFFAOYSA-N
SMILES	CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)Cl)OCC)C
PubChem CID	135496216

Physical properties
Physical form	Solid
LogP (XLogP3)	2.5
H-bond donors / acceptors	1 / 6
TPSA	111 Å²
Synonyms	Sildenafil Chlorosulfonyl Impurity, Sildenafil Chlorosulfone, Sildenafil chlorosulfonyl, Sildenafil Impurity 7, 4-e

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H413May cause long lasting harmful effects to aquatic life

Precautionary statements: P260, P261, P264, P264 + P265, P271, P273, P280, P301 + P330 + P331, P302 + P352, P302 + P361 + P354, P304 + P340, P305 + P351 + P338, P305 + P354 + P338, P316, P319, P321, P332 + P317, P337 + P317, P362 + P364, P363, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sildenafil Chlorosulfone Impurity?

The CAS Registry Number of Sildenafil Chlorosulfone Impurity is 139756-22-2. It is also known as Sildenafil Chlorosulfonyl Impurity, Sildenafil Chlorosulfone, Sildenafil chlorosulfonyl.

What is the molecular formula and molecular weight of Sildenafil Chlorosulfone Impurity?

Sildenafil Chlorosulfone Impurity has the molecular formula C17H19ClN4O4S and a molecular weight of 410.9 g/mol. Its IUPAC name is 4-ethoxy-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)benzenesulfonyl chloride.

What is Sildenafil Chlorosulfone Impurity used for?

Sildenafil Chlorosulfone Impurity is supplied as a characterised reference material related to Sildenafil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sildenafil Chlorosulfone Impurity can I order?

We supply Sildenafil Chlorosulfone Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sildenafil Chlorosulfone Impurity?

Yes. Every lot of Sildenafil Chlorosulfone Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sildenafil Chlorosulfone Impurity be shipped internationally?

Yes. Sildenafil Chlorosulfone Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.