Simethicone

Name: Simethicone
Brand: Vaqora Chemicals
SKU: VQ-028031

About Simethicone

Simethicone is a high-purity reference standard of Simethicone carrying the CAS registry number 8050-81-5. With the molecular formula C6H18O4Si3, it has a molar mass of 238.46 g/mol. It is also known as Simeticone or Sentry Simethicone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Simethicone, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Simethicone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Simethicone

View every impurity, metabolite and intermediate we list for Simethicone.

Simethicone impurities

Specifications & identifiers

Chemical identifiers
Product name	Simethicone
Catalogue No.	VQ-028031
CAS Number	8050-81-5
IUPAC name	dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane
Molecular formula	C₆H₁₈O₄Si₃
Molecular weight	238.46 g/mol
Exact mass	238.0513
Grade	Reference Standard
HSN code	38229090
InChIKey	AMTWCFIAVKBGOD-UHFFFAOYSA-N
SMILES	CO[Si](C)(C)O[Si](C)(C)C.O=[Si]=O
PubChem CID	6433516

Physical properties
Physical form	Solid
H-bond donors / acceptors	0 / 4
TPSA	52.6 Å²
Synonyms	Simeticone, Sentry Simethicone, Mylanta Gas Relief, Mylicon Infant's Drops, Sentry Simethicone Emulsion, Simethicone(200), Simethicone(500), Simethicone-Viscosity 500cP

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Signal word: Danger

Hazard statements

H225Highly flammable liquid and vapor
H319Causes serious eye irritation
H335May cause respiratory irritation
H336May cause drowsiness or dizziness

Precautionary statements: P210, P233, P240, P241, P242, P243, P261, P264 + P265, P271, P280, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P319, P337 + P317, P370 + P378, P403 + P233, P403 + P235, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Simethicone?

The CAS Registry Number of Simethicone is 8050-81-5. It is also known as Simeticone, Sentry Simethicone, Mylanta Gas Relief.

What is the molecular formula and molecular weight of Simethicone?

Simethicone has the molecular formula C6H18O4Si3 and a molecular weight of 238.46 g/mol.

What is Simethicone used for?

Simethicone is supplied as a characterised reference material related to Simethicone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Simethicone can I order?

We supply Simethicone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Simethicone?

Yes. Every lot of Simethicone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Simethicone be shipped internationally?

Yes. Simethicone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.