Simvastatin Methyl Ester

Name: Simvastatin Methyl Ester
Brand: Vaqora Chemicals
SKU: VQ-028038

About Simvastatin Methyl Ester

Vaqora Chemicals supplies Simvastatin Methyl Ester, an impurity of Simvastatin registered under CAS number 145576-26-7. Its molecular formula is C26H42O6 and its molecular weight is 450.6 g/mol. It is also known as Tenivastatin Methyl Ester or Simvastatin Acid Methyl Ester.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Simvastatin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Simvastatin

View every impurity, metabolite and intermediate we list for Simvastatin.

Simvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Simvastatin Methyl Ester
Catalogue No.	VQ-028038
CAS Number	145576-26-7
IUPAC name	methyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
Molecular formula	C₂₆H₄₂O₆
Molecular weight	450.6 g/mol
Exact mass	450.2981
Grade	Reference Standard
HSN code	38229090
InChIKey	ANVXHKJGHXLLPK-RVTXAWHXSA-N
SMILES	CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)OC)O)O)C
PubChem CID	11048644

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	2 / 6
TPSA	93.1 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Simvastatin Methyl Ester?

The CAS Registry Number of Simvastatin Methyl Ester is 145576-26-7. It is also known as Tenivastatin Methyl Ester, Simvastatin Acid Methyl Ester, Simvastatin Hydroxy Acid Methyl Ester.

What is the molecular formula and molecular weight of Simvastatin Methyl Ester?

Simvastatin Methyl Ester has the molecular formula C26H42O6 and a molecular weight of 450.6 g/mol. Its IUPAC name is methyl (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate.

What is Simvastatin Methyl Ester used for?

Simvastatin Methyl Ester is supplied as a characterised reference material related to Simvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Simvastatin Methyl Ester can I order?

We supply Simvastatin Methyl Ester in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Simvastatin Methyl Ester?

Yes. Every lot of Simvastatin Methyl Ester is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Simvastatin Methyl Ester be shipped internationally?

Yes. We export Simvastatin Methyl Ester worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.