Sitagliptin 2-Desfluoro Impurity

Name: Sitagliptin 2-Desfluoro Impurity
Brand: Vaqora Chemicals
SKU: VQ-023764

About Sitagliptin 2-Desfluoro Impurity

Sitagliptin 2-Desfluoro Impurity is an impurity of Sitagliptin carrying the CAS registry number 486459-88-5. With the molecular formula C16H16F5N5O, it has a molar mass of 389.32 g/mol. Alternative names: 2-Desfluoro Sitagliptin.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

This Sitagliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sitagliptin 2-Desfluoro Impurity in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin 2-Desfluoro Impurity
Catalogue No.	VQ-023764
CAS Number	486459-88-5
IUPAC name	(3R)-3-amino-4-(3,4-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one
Molecular formula	C₁₆H₁₆F₅N₅O
Molecular weight	389.32 g/mol
Exact mass	389.1275
Grade	Reference Standard
HSN code	38229090
InChIKey	VZQYRRVZSLWCAA-SNVBAGLBSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3)F)F)N
PubChem CID	10157141

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	1 / 9
TPSA	77 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin 2-Desfluoro Impurity?

The CAS Registry Number of Sitagliptin 2-Desfluoro Impurity is 486459-88-5. It is also known as 2-Desfluoro Sitagliptin.

What is the molecular formula and molecular weight of Sitagliptin 2-Desfluoro Impurity?

Sitagliptin 2-Desfluoro Impurity has the molecular formula C16H16F5N5O and a molecular weight of 389.32 g/mol. Its IUPAC name is (3R)-3-amino-4-(3,4-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one.

What is Sitagliptin 2-Desfluoro Impurity used for?

Sitagliptin 2-Desfluoro Impurity is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin 2-Desfluoro Impurity can I order?

We supply Sitagliptin 2-Desfluoro Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin 2-Desfluoro Impurity?

Yes. Every lot of Sitagliptin 2-Desfluoro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin 2-Desfluoro Impurity be shipped internationally?

Yes. We export Sitagliptin 2-Desfluoro Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.