Sitagliptin Impurity 22

Name: Sitagliptin Impurity 22
Brand: Vaqora Chemicals
SKU: VQ-033884

About Sitagliptin Impurity 22

Sitagliptin Impurity 22 is an impurity of Sitagliptin carrying the CAS registry number 945261-50-7. Its molecular formula is C16H15F6N5O and its molecular weight is 407.31 g/mol. Common synonyms include 4,5-Desfluoro-2,3-difluoro sitagliptin.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Sitagliptin, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Sitagliptin Impurity 22 in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sitagliptin

View every impurity, metabolite and intermediate we list for Sitagliptin.

Sitagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Sitagliptin Impurity 22
Catalogue No.	VQ-033884
CAS Number	945261-50-7
IUPAC name	(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,3,6-trifluorophenyl)butan-1-one
Molecular formula	C₁₆H₁₅F₆N₅O
Molecular weight	407.31 g/mol
Exact mass	407.1181
Grade	Reference Standard
HSN code	38229090
InChIKey	QYCBJMPVGAGUAX-MRVPVSSYSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3F)F)F)N
PubChem CID	44431176

Physical properties
Physical form	Solid
LogP (XLogP3)	0.7
H-bond donors / acceptors	1 / 10
TPSA	77 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sitagliptin Impurity 22?

The CAS Registry Number of Sitagliptin Impurity 22 is 945261-50-7. It is also known as 4,5-Desfluoro-2,3-difluoro sitagliptin.

What is the molecular formula and molecular weight of Sitagliptin Impurity 22?

Sitagliptin Impurity 22 has the molecular formula C16H15F6N5O and a molecular weight of 407.31 g/mol. Its IUPAC name is (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,3,6-trifluorophenyl)butan-1-one.

What is Sitagliptin Impurity 22 used for?

Sitagliptin Impurity 22 is supplied as a characterised reference material related to Sitagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sitagliptin Impurity 22 can I order?

We supply Sitagliptin Impurity 22 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sitagliptin Impurity 22?

Yes. Every lot of Sitagliptin Impurity 22 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sitagliptin Impurity 22 be shipped internationally?

Yes. We export Sitagliptin Impurity 22 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.