Sorafenib Impurity H

Name: Sorafenib Impurity H
Brand: Vaqora Chemicals
SKU: VQ-005948

About Sorafenib Impurity H

Sorafenib Impurity H (CAS 1431697-81-2) is an impurity of Sorafenib offered by Vaqora Chemicals. Its molecular formula is C21H16ClF3N4O3 and its molecular weight is 464.8 g/mol. Systematically, it is named 4-[4-[[2-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide. Alternative names: 4-Deschloro-2-chloro-Sorafenib and Sorafenib Related Compound 20.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

This Sorafenib impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sorafenib Impurity H is dispatched with a Certificate of Analysis (COA) to destinations worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Sorafenib

View every impurity, metabolite and intermediate we list for Sorafenib.

Sorafenib impurities

Specifications & identifiers

Chemical identifiers
Product name	Sorafenib Impurity H
Catalogue No.	VQ-005948
CAS Number	1431697-81-2
IUPAC name	4-[4-[[2-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
Molecular formula	C₂₁H₁₆ClF₃N₄O₃
Molecular weight	464.8 g/mol
Exact mass	464.0863
Grade	Reference Standard
HSN code	38229090
InChIKey	JWAKXXCHFJSKRN-UHFFFAOYSA-N
SMILES	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC=CC(=C3Cl)C(F)(F)F
PubChem CID	118703724

Physical properties
Physical form	Solid
LogP (XLogP3)	4.1
H-bond donors / acceptors	3 / 7
TPSA	92.4 Å²
Synonyms	4-Deschloro-2-chloro-Sorafenib, 4-(4-(3-(2-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide, Sorafenib Related Compound 20, Sorafenib Impurity, Sorafenib Tosylate Impurity F, starbld0000680, Sorafenib EP Impurity H, CS-Z0001

Safety & hazard information (GHS)

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H362May cause harm to breast-fed children
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P263, P264, P270, P273, P280, P318, P319, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sorafenib Impurity H?

The CAS Registry Number of Sorafenib Impurity H is 1431697-81-2. It is also known as 4-Deschloro-2-chloro-Sorafenib, 4-(4-(3-(2-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamide, Sorafenib Related Compound 20.

What is the molecular formula and molecular weight of Sorafenib Impurity H?

Sorafenib Impurity H has the molecular formula C21H16ClF3N4O3 and a molecular weight of 464.8 g/mol. Its IUPAC name is 4-[4-[[2-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide.

What is Sorafenib Impurity H used for?

Sorafenib Impurity H is supplied as a characterised reference material related to Sorafenib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sorafenib Impurity H can I order?

We supply Sorafenib Impurity H in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sorafenib Impurity H?

Yes. Every lot of Sorafenib Impurity H is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sorafenib Impurity H be shipped internationally?

Yes. Sorafenib Impurity H is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.