Sotorasib

Name: Sotorasib
Brand: Vaqora Chemicals
SKU: VQ-023793

About Sotorasib

Listed under CAS 2296729-00-3, Sotorasib is a high-purity reference standard of Sotorasib available from Vaqora Chemicals. With the molecular formula C30H30F2N6O3, it has a molar mass of 560.6 g/mol. It is also known as AMG-510 or AMG 510.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a reference sample of Sotorasib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Sotorasib is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Sotorasib

View every impurity, metabolite and intermediate we list for Sotorasib.

Sotorasib impurities

Specifications & identifiers

Chemical identifiers
Product name	Sotorasib
Catalogue No.	VQ-023793
CAS Number	2296729-00-3
IUPAC name	6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-yl-3-pyridinyl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one
Molecular formula	C₃₀H₃₀F₂N₆O₃
Molecular weight	560.6 g/mol
Exact mass	560.2347
Grade	Reference Standard
HSN code	38229090
InChIKey	NXQKSXLFSAEQCZ-SFHVURJKSA-N
SMILES	C[C@H]1CN(CCN1C2=NC(=O)N(C3=NC(=C(C=C32)F)C4=C(C=CC=C4F)O)C5=C(C=CN=C5C(C)C)C)C(=O)C=C
PubChem CID	137278711

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 7
TPSA	102 Å²
Synonyms	AMG-510, AMG 510, Kras G12C inhibitor 9, Kras mutant-targeting AMG 510, AMG-510 racemate, Sotorasib (AMG510) racemate, (S)-AMG-510, AMG510 racemate, Sotorasib isomer, (1m)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-(propan-2-yl)pyridin-3-yl)-, AMG-510(racemate)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Sotorasib?

The CAS Registry Number of Sotorasib is 2296729-00-3. It is also known as AMG-510, AMG 510, Kras G12C inhibitor 9.

What is the molecular formula and molecular weight of Sotorasib?

Sotorasib has the molecular formula C30H30F2N6O3 and a molecular weight of 560.6 g/mol. Its IUPAC name is 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-yl-3-pyridinyl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one.

What is Sotorasib used for?

Sotorasib is supplied as a characterised reference material related to Sotorasib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Sotorasib can I order?

We supply Sotorasib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Sotorasib?

Yes. Every lot of Sotorasib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Sotorasib be shipped internationally?

Yes. We export Sotorasib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.