Tafluprost Acid

Name: Tafluprost Acid
Brand: Vaqora Chemicals
SKU: VQ-028351

About Tafluprost Acid

Tafluprost Acid is an impurity of Tafluprost carrying the CAS registry number 209860-88-8. Formula C22H28F2O5, molecular weight 410.5 g/mol. Its systematic (IUPAC) name is (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid. Common synonyms include AFP-172 and Tafluprost (free acid).

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 2 hazard statements. Review the Safety Data Sheet before use.

This Tafluprost impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tafluprost

View every impurity, metabolite and intermediate we list for Tafluprost.

Tafluprost impurities

Specifications & identifiers

Chemical identifiers
Product name	Tafluprost Acid
Catalogue No.	VQ-028351
CAS Number	209860-88-8
IUPAC name	(Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid
Molecular formula	C₂₂H₂₈F₂O₅
Molecular weight	410.5 g/mol
Exact mass	410.1905
Grade	Reference Standard
HSN code	38229090
InChIKey	KIQXRQVVYTYYAZ-VKVYFNERSA-N
SMILES	C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/C(COC2=CC=CC=C2)(F)F)C/C=C\CCCC(=O)O)O
PubChem CID	9978917

Physical properties
Physical form	Solid
LogP (XLogP3)	3.3
H-bond donors / acceptors	3 / 7
TPSA	87 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tafluprost Acid?

The CAS Registry Number of Tafluprost Acid is 209860-88-8. It is also known as AFP-172, Tafluprost (free acid), Taluprost acid.

What is the molecular formula and molecular weight of Tafluprost Acid?

Tafluprost Acid has the molecular formula C22H28F2O5 and a molecular weight of 410.5 g/mol. Its IUPAC name is (Z)-7-[(1R,2R,3R,5S)-2-[(E)-3,3-difluoro-4-phenoxybut-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid.

What is Tafluprost Acid used for?

Tafluprost Acid is supplied as a characterised reference material related to Tafluprost. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tafluprost Acid can I order?

We supply Tafluprost Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tafluprost Acid?

Yes. Every lot of Tafluprost Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tafluprost Acid be shipped internationally?

Yes. Tafluprost Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.