Tenofovir Alafenamide Fumarate

Name: Tenofovir Alafenamide Fumarate
Brand: Vaqora Chemicals
SKU: VQ-028265

About Tenofovir Alafenamide Fumarate

Vaqora Chemicals supplies Tenofovir Alafenamide Fumarate, an impurity of Tenofovir registered under CAS number 379270-38-9. Formula C25H33N6O9P, molecular weight 592.5 g/mol. It is also known as GS-7340 monofumarate or Tenofovir alafenamide monofumarate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a characterised impurity of Tenofovir, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Tenofovir Alafenamide Fumarate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tenofovir

View every impurity, metabolite and intermediate we list for Tenofovir.

Tenofovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Tenofovir Alafenamide Fumarate
Catalogue No.	VQ-028265
CAS Number	379270-38-9
IUPAC name	(E)-but-2-enedioic acid;propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
Molecular formula	C₂₅H₃₃N₆O₉P
Molecular weight	592.5 g/mol
Exact mass	592.2047
Grade	Reference Standard
HSN code	38229090
InChIKey	MEJAFWXKUKMUIR-FHPNUNMMSA-N
SMILES	C[C@H](CN1C=NC2=C(N=CN=C21)N)OC[P@@](=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=CC=C3.C(=C/C(=O)O)\C(=O)O
PubChem CID	68516365

Physical properties
Physical form	Solid
H-bond donors / acceptors	4 / 14
TPSA	218 Å²
Synonyms	GS-7340 monofumarate, Tenofovir alafenamide monofumarate, GS-7340 fumarate, GS-7340 (fumarate), TAF fumarate, GS-7339 monofumarate, Tenofovir alafenamide monofumarate (USAN)

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P260, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tenofovir Alafenamide Fumarate?

The CAS Registry Number of Tenofovir Alafenamide Fumarate is 379270-38-9. It is also known as GS-7340 monofumarate, Tenofovir alafenamide monofumarate, GS-7340 fumarate.

What is the molecular formula and molecular weight of Tenofovir Alafenamide Fumarate?

Tenofovir Alafenamide Fumarate has the molecular formula C25H33N6O9P and a molecular weight of 592.5 g/mol.

What is Tenofovir Alafenamide Fumarate used for?

Tenofovir Alafenamide Fumarate is supplied as a characterised reference material related to Tenofovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tenofovir Alafenamide Fumarate can I order?

We supply Tenofovir Alafenamide Fumarate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tenofovir Alafenamide Fumarate?

Yes. Every lot of Tenofovir Alafenamide Fumarate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tenofovir Alafenamide Fumarate be shipped internationally?

Yes. Tenofovir Alafenamide Fumarate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.