Tenofovir diphosphate

Name: Tenofovir diphosphate
Brand: Vaqora Chemicals
SKU: VQ-034907

About Tenofovir diphosphate

Tenofovir diphosphate is an impurity of Tenofovir carrying the CAS registry number 166403-66-3. Its molecular formula is C9H16N5O10P3 and its molecular weight is 447.17 g/mol. Its systematic (IUPAC) name is [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid. It is also known as N-Tenofovir Diphosphate or Tenofovir-DP.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Tenofovir to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Tenofovir diphosphate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Tenofovir

View every impurity, metabolite and intermediate we list for Tenofovir.

Tenofovir impurities

Specifications & identifiers

Chemical identifiers
Product name	Tenofovir diphosphate
Catalogue No.	VQ-034907
CAS Number	166403-66-3
IUPAC name	[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid
Molecular formula	C₉H₁₆N₅O₁₀P₃
Molecular weight	447.17 g/mol
Exact mass	447.011
Grade	Reference Standard
HSN code	38229090
InChIKey	IACQCQDWSIQSRP-ZCFIWIBFSA-N
SMILES	C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)OP(=O)(O)OP(=O)(O)O
PubChem CID	5481180

Physical properties
Physical form	Solid
LogP (XLogP3)	-3.8
H-bond donors / acceptors	5 / 14
TPSA	229 Å²
Synonyms	N-Tenofovir Diphosphate, (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic diphosphoric anhydride, Tenofovir-DP, PMPA diphosphate, Tenofovir diphosphate, PMPA-diphosphate, PMPApp, Tenofovir diphosphate triethylamine(mixture of diastereomers)

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tenofovir diphosphate?

The CAS Registry Number of Tenofovir diphosphate is 166403-66-3. It is also known as N-Tenofovir Diphosphate, (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonic diphosphoric anhydride, Tenofovir-DP.

What is the molecular formula and molecular weight of Tenofovir diphosphate?

Tenofovir diphosphate has the molecular formula C9H16N5O10P3 and a molecular weight of 447.17 g/mol. Its IUPAC name is [(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid.

What is Tenofovir diphosphate used for?

Tenofovir diphosphate is supplied as a characterised reference material related to Tenofovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tenofovir diphosphate can I order?

We supply Tenofovir diphosphate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tenofovir diphosphate?

Yes. Every lot of Tenofovir diphosphate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tenofovir diphosphate be shipped internationally?

Yes. We export Tenofovir diphosphate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.