tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carbo… 223644-10-8

Name: tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate
Brand: Vaqora Chemicals
SKU: VQ-033562

About tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate

Listed under CAS 223644-10-8, tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate is an impurity of Ripasudil available from Vaqora Chemicals. Its molecular formula is C11H22N2O2 and its molecular weight is 214.3 g/mol. Its systematic (IUPAC) name is tert-butyl (3R)-3-methyl-1,4-diazepane-1-carboxylate. It is also known as (R)-1-Boc-3-methyl-1,4-diazepane.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Ripasudil to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ripasudil

View every impurity, metabolite and intermediate we list for Ripasudil.

Ripasudil impurities

Specifications & identifiers

Chemical identifiers
Product name	tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate
Catalogue No.	VQ-033562
CAS Number	223644-10-8
IUPAC name	tert-butyl (3R)-3-methyl-1,4-diazepane-1-carboxylate
Molecular formula	C₁₁H₂₂N₂O₂
Molecular weight	214.3 g/mol
Exact mass	214.1681
Grade	Reference Standard
HSN code	38229090
InChIKey	GDTFCUXOVITPHU-SECBINFHSA-N
SMILES	C[C@@H]1CN(CCCN1)C(=O)OC(C)(C)C
PubChem CID	29980997

Physical properties
Physical form	Solid
LogP (XLogP3)	1.2
H-bond donors / acceptors	1 / 3
TPSA	41.6 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate?

The CAS Registry Number of tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate is 223644-10-8. It is also known as (3R)-Hexahydro-3-methyl-1H-1,4-diazepine-1-carboxylic acid tert-butyl ester, (R)-1-Boc-3-methyl-1,4-diazepane.

What is the molecular formula and molecular weight of tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate?

tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate has the molecular formula C11H22N2O2 and a molecular weight of 214.3 g/mol. Its IUPAC name is tert-butyl (3R)-3-methyl-1,4-diazepane-1-carboxylate.

What is tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate used for?

tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate is supplied as a characterised reference material related to Ripasudil. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate can I order?

We supply tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate?

Yes. Every lot of tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate be shipped internationally?

Yes. tert-Butyl (R)-3-Methyl-1,4-diazepane-1-carboxylate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.