tert-Butyldimethylsilyl Chloride

Name: tert-Butyldimethylsilyl Chloride
Brand: Vaqora Chemicals
SKU: VQ-011144

About tert-Butyldimethylsilyl Chloride

tert-Butyldimethylsilyl Chloride is an organosilicon compound carrying the CAS registry number 18162-48-6. The compound has the formula C6H15ClSi, corresponding to a molecular weight of 150.72 g/mol. Its systematic (IUPAC) name is tert-butyl-chloro-dimethylsilane. It is also known as Tert-Butyldimethylsilyl Chloride(TBDMSCl) or Chloro(1,1-dimethylethyl)dimethyl-silane.

Store sealed in a dry, well-ventilated location away from incompatible materials. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

Key uses span organic synthesis and API synthesis. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer tert-Butyldimethylsilyl Chloride in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. SDS and detailed specification sheets can be requested with your quotation. Larger quantities and custom packaging are available. Request a quote for pricing and lead time.

Typical applications

Organic synthesis
API synthesis

Industries

Specifications & identifiers

Chemical identifiers
Product name	tert-Butyldimethylsilyl Chloride
Catalogue No.	VQ-011144
CAS Number	18162-48-6
IUPAC name	tert-butyl-chloro-dimethylsilane
Molecular formula	C₆H₁₅ClSi
Molecular weight	150.72 g/mol
Exact mass	150.0632
Grade	Reference Standard
InChIKey	BCNZYOJHNLTNEZ-UHFFFAOYSA-N
SMILES	CC(C)(C)[Si](C)(C)Cl
PubChem CID	28928

Physical properties
Physical form	Other
H-bond donors / acceptors	0 / 0
TPSA	0 Å²
Synonyms	Tert-Butyldimethylsilyl Chloride(TBDMSCl), Chloro(1,1-dimethylethyl)dimethyl-silane, Chloro-tert-butyldimethyl-silane, (1,1-Dimethylethyl)dimethylsilyl Chloride, Chlorodimethyl-tert-butylsilane, TBDMS, tert-Butyl(dimethyl)silane Chloride, tert-Butyldimethylchlorosilane, TBS-Cl, TBSCl, tert-Butylchlorodimethylsilane, t-Butyldimethylchlorosilane

Safety & hazard information (GHS)

Flammable

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H228Flammable solid
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H335May cause respiratory irritation
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P210, P240, P241, P260, P261, P264, P264 + P265, P271, P273, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P317, P319, P321, P363, P370 + P378, P391, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Other grades of CAS 18162-48-6

Synthesis

tert-Butyldimethylsilyl chloride, 99%

CAS: 18162-48-6
Formula: C₆H₁₅ClSi
MW: 150.72 g/mol

VQ-000990

AR

tert-Butyldimethylsilyl Chloride, AR

CAS: 18162-48-6
Formula: C₆H₁₅ClSi
MW: 150.72 g/mol

VQ-047176

Frequently asked questions

What is the CAS number of tert-Butyldimethylsilyl Chloride?

The CAS Registry Number of tert-Butyldimethylsilyl Chloride is 18162-48-6. It is also known as Tert-Butyldimethylsilyl Chloride(TBDMSCl), Chloro(1,1-dimethylethyl)dimethyl-silane, Chloro-tert-butyldimethyl-silane.

What is the molecular formula and molecular weight of tert-Butyldimethylsilyl Chloride?

tert-Butyldimethylsilyl Chloride has the molecular formula C6H15ClSi and a molecular weight of 150.72 g/mol. Its IUPAC name is tert-butyl-chloro-dimethylsilane.

Which grade and pack sizes of tert-Butyldimethylsilyl Chloride can I order?

We supply tert-Butyldimethylsilyl Chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with tert-Butyldimethylsilyl Chloride?

Yes. Every lot of tert-Butyldimethylsilyl Chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can tert-Butyldimethylsilyl Chloride be shipped internationally?

Yes. tert-Butyldimethylsilyl Chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.