Tertrahydroisoquin-3-carboxylic acid

Name: Tertrahydroisoquin-3-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-041797

About Tertrahydroisoquin-3-carboxylic acid

Vaqora Chemicals supplies Tertrahydroisoquin-3-carboxylic acid, an impurity of Quinapril registered under CAS number 67123-97-1. Formula C10H11NO2, molecular weight 177.2 g/mol. The IUPAC name is 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid. Common synonyms include Tetrahydro-3-isoquinoline carboxylic acid and 3-carboxy-1,2,3,4-tetrahydroisoquinoline.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Quinapril to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Tertrahydroisoquin-3-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Quinapril

View every impurity, metabolite and intermediate we list for Quinapril.

Quinapril impurities

Specifications & identifiers

Chemical identifiers
Product name	Tertrahydroisoquin-3-carboxylic acid
Catalogue No.	VQ-041797
CAS Number	67123-97-1
IUPAC name	1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
Molecular formula	C₁₀H₁₁NO₂
Molecular weight	177.2 g/mol
Exact mass	177.079
Grade	Reference Standard
HSN code	38229090
InChIKey	BWKMGYQJPOAASG-UHFFFAOYSA-N
SMILES	C1C(NCC2=CC=CC=C21)C(=O)O
PubChem CID	95489

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.3
H-bond donors / acceptors	2 / 3
TPSA	49.3 Å²
Synonyms	3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, 1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, Tetrahydro-3-isoquinoline carboxylic acid, rac 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid, 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid, (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-Carboxylic Acid, 3-carboxy-1,2,3,4-tetrahydroisoquinoline, Tic-AA, 1,2,3,4-tetra-hydroisoq, tetrahydroisoquinoline 3-carboxylic acid, tetrahydroisoquinoline-3-carboxylic acid, 1234-Tetrahydroisoquinoline-3-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tertrahydroisoquin-3-carboxylic acid?

The CAS Registry Number of Tertrahydroisoquin-3-carboxylic acid is 67123-97-1. It is also known as 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-, 1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid, Tetrahydro-3-isoquinoline carboxylic acid.

What is the molecular formula and molecular weight of Tertrahydroisoquin-3-carboxylic acid?

Tertrahydroisoquin-3-carboxylic acid has the molecular formula C10H11NO2 and a molecular weight of 177.2 g/mol. Its IUPAC name is 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid.

What is Tertrahydroisoquin-3-carboxylic acid used for?

Tertrahydroisoquin-3-carboxylic acid is supplied as a characterised reference material related to Quinapril. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tertrahydroisoquin-3-carboxylic acid can I order?

We supply Tertrahydroisoquin-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tertrahydroisoquin-3-carboxylic acid?

Yes. Every lot of Tertrahydroisoquin-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tertrahydroisoquin-3-carboxylic acid be shipped internationally?

Yes. Tertrahydroisoquin-3-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.