Thalidomide

Name: Thalidomide
Brand: Vaqora Chemicals
SKU: VQ-013822

About Thalidomide

Vaqora Chemicals supplies Thalidomide, a process intermediate or related compound of Pomalidomide registered under CAS number 50-35-1. Its molecular formula is C13H10N2O4 and its molecular weight is 258.23 g/mol. The IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. It is also known as 3-Phthalimidoglutarimide or Celgene.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Pomalidomide, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Thalidomide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Pomalidomide

View every impurity, metabolite and intermediate we list for Pomalidomide.

Pomalidomide impurities

Specifications & identifiers

Chemical identifiers
Product name	Thalidomide
Catalogue No.	VQ-013822
CAS Number	50-35-1
IUPAC name	2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular formula	C₁₃H₁₀N₂O₄
Molecular weight	258.23 g/mol
Exact mass	258.0641
Grade	Reference Standard
HSN code	2933
InChIKey	UEJJHQNACJXSKW-UHFFFAOYSA-N
SMILES	C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O
PubChem CID	5426

Physical properties
Physical form	Solid
LogP (XLogP3)	0.3
H-bond donors / acceptors	1 / 4
TPSA	83.6 Å²
Synonyms	2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione, 2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, 3-Phthalimidoglutarimide, Celgene, Contergan, Distaval, Immunoprin, K 17, Kevadon, Myrin, N-(2,6-Dioxo-3-piperidinyl)phthalimide, Neurosedyn

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H360May damage fertility or the unborn child

Precautionary statements: P203, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thalidomide?

The CAS Registry Number of Thalidomide is 50-35-1. It is also known as 2-(2,6-Dioxopiperidin-3-yl)isoindoline-1,3-dione, 2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, 3-Phthalimidoglutarimide.

What is the molecular formula and molecular weight of Thalidomide?

Thalidomide has the molecular formula C13H10N2O4 and a molecular weight of 258.23 g/mol. Its IUPAC name is 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione.

What is Thalidomide used for?

Thalidomide is supplied as a characterised reference material related to Pomalidomide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thalidomide can I order?

We supply Thalidomide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thalidomide?

Yes. Every lot of Thalidomide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thalidomide be shipped internationally?

Yes. Thalidomide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.