Thiotepa

Name: Thiotepa
Brand: Vaqora Chemicals
SKU: VQ-028341

About Thiotepa

Thiotepa is a high-purity reference standard of Thiotepa carrying the CAS registry number 52-24-4. With the molecular formula C6H12N3PS, it has a molar mass of 189.22 g/mol. Systematically, it is named tris(aziridin-1-yl)-sulfanylidene-lambda5-phosphane. Alternative names: Triethylenethiophosphoramide and Thiophosphamide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a reference sample of Thiotepa, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Thiotepa

View every impurity, metabolite and intermediate we list for Thiotepa.

Thiotepa impurities

Specifications & identifiers

Chemical identifiers
Product name	Thiotepa
Catalogue No.	VQ-028341
CAS Number	52-24-4
IUPAC name	tris(aziridin-1-yl)-sulfanylidene-lambda5-phosphane
Molecular formula	C₆H₁₂N₃PS
Molecular weight	189.22 g/mol
Exact mass	189.049
Grade	Reference Standard
HSN code	38229090
InChIKey	FOCVUCIESVLUNU-UHFFFAOYSA-N
SMILES	C1CN1P(=S)(N2CC2)N3CC3
PubChem CID	5453

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	0 / 4
TPSA	41.1 Å²
Synonyms	Triethylenethiophosphoramide, Thiophosphamide, Tespamin, Tespamine, Tifosyl, Tris(1-aziridinyl)phosphine sulfide, Thiotriethylenephosphoramide, Tris(ethylenimino)thiophosphate, Triethylene thiophosphoramide, N,N',N''-Triethylenethiophosphoramide, Triaziridinylphosphine sulfide, Triethylenethiophosphorotriamide

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H300Fatal if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H360May damage fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Thiotepa?

The CAS Registry Number of Thiotepa is 52-24-4. It is also known as Triethylenethiophosphoramide, Thiophosphamide, Tespamin.

What is the molecular formula and molecular weight of Thiotepa?

Thiotepa has the molecular formula C6H12N3PS and a molecular weight of 189.22 g/mol. Its IUPAC name is tris(aziridin-1-yl)-sulfanylidene-lambda5-phosphane.

What is Thiotepa used for?

Thiotepa is supplied as a characterised reference material related to Thiotepa. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Thiotepa can I order?

We supply Thiotepa in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Thiotepa?

Yes. Every lot of Thiotepa is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Thiotepa be shipped internationally?

Yes. Thiotepa is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.