Timolol

Name: Timolol
Brand: Vaqora Chemicals
SKU: VQ-007799

About Timolol

Timolol is a high-purity reference standard of Timolol carrying the CAS registry number 26839-75-8. Formula C13H24N4O3S, molecular weight 316.42 g/mol. The IUPAC name is (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol. It is also known as (S)-Timolol or Arutimol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 5 hazard statements. Review the Safety Data Sheet before use.

As a reference sample of Timolol, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Timolol

View every impurity, metabolite and intermediate we list for Timolol.

Timolol impurities

Specifications & identifiers

Chemical identifiers
Product name	Timolol
Catalogue No.	VQ-007799
CAS Number	26839-75-8
Other CAS	26921-17-5
IUPAC name	(2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
Molecular formula	C₁₃H₂₄N₄O₃S
Molecular weight	316.42 g/mol
Exact mass	316.1569
Grade	Reference Standard
HSN code	38229090
InChIKey	BLJRIMJGRPQVNF-JTQLQIEISA-N
SMILES	CC(C)(C)NC[C@@H](COC1=NSN=C1N2CCOCC2)O
PubChem CID	33624

Physical properties
Physical form	Solid
LogP (XLogP3)	1.8
H-bond donors / acceptors	2 / 8
TPSA	108 Å²
Synonyms	(S)-Timolol, Arutimol, L-Timolol, Oftensin, (S)-1-(tert-Butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, (S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol, (S)-(-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole, Betimol, Timolol anhydrous, (-)-3-Morpholino-4-(3-tert-butylamino-2-hydroxypropoxy)-1,2,5-thiadiazole, S-(-)-3-(3-tert-Butylamino-2-hydroxypropoxy)-4-morpholino-1,2,5-thiadiazole, Glau-opt

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children

Precautionary statements: P203, P260, P263, P264, P270, P280, P301 + P317, P318, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Timolol?

The CAS Registry Number of Timolol is 26839-75-8. It is also known as (S)-Timolol, Arutimol, L-Timolol.

What is the molecular formula and molecular weight of Timolol?

Timolol has the molecular formula C13H24N4O3S and a molecular weight of 316.42 g/mol. Its IUPAC name is (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol.

What is Timolol used for?

Timolol is supplied as a characterised reference material related to Timolol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Timolol can I order?

We supply Timolol in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Timolol?

Yes. Every lot of Timolol is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Timolol be shipped internationally?

Yes. Timolol is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.